The sodium/hydrogen exchange system in cardiac cells: its biochemical and pharmacological properties and its role in regulating internal concentrations of sodium …

M Lazdunski, C Frelin, P Vigne - Journal of molecular and cellular …, 1985 - Elsevier
This paper describes the properties of the amiloride-sensitive Na + /H + antiporter in chick
cardiac cells, compares them with those known in other cellular systems and analyzes the role …

The regulation of the intracellular pH in cells from vertebrates

C Frelin, P Vigne, A Ladoux… - European journal of …, 1988 - Wiley Online Library
… The upper panel shows the sequence of events that follows membrane receptor
occupancy by agonists of phospholipase C and that lead to an increased activity of the Na+/H+ …

Self-renewal as a therapeutic target in human colorectal cancer

…, NM Pedley, E Lima-Fernandes, C Frelin… - Nature medicine, 2014 - nature.com
… (c) The percentage of cells expressing eGFP among human colorectal cancer cells transduced
with the shBMI-1 or shLUC virus and passaged every 4–7 d. For LS174T cells, data are …

[HTML][HTML] A new member of the natriuretic peptide family is present in the venom of the green mamba (Dendroaspis angusticeps).

H Schweitz, P Vigne, D Moinier, C Frelin… - Journal of Biological …, 1992 - Elsevier
This paper describes the purification, sequence, and biological properties of a 38-amino
acid residue peptide from the venom of Dendroaspis angusticeps which shared important …

Amiloride and its analogs as tools to inhibit Na+ transport via the Na+ channel, the Na+/H+ antiport and the Na+/Ca2+ exchanger

C Frelin, P Barbry, P Vigne, O Chassande… - Biochimie, 1988 - Elsevier
C, Dose-response curves for the inhibition of cardiac Na t IH + antipori by benzamil (Benz.,
E), amiioride (Ami., ¥), dimethyiamiioride (DMA, e) and ethyiisopropyiamiioride (EIPA, A) from …

[PDF][PDF] CDK6 levels regulate quiescence exit in human hematopoietic stem cells

E Laurenti, C Frelin, S Xie, R Ferrari, CF Dunant… - Cell stem cell, 2015 - cell.com
… (C) Cell diameter of indicated populations measured with ImageJ from microscopy pictures.
n > 323 cells from four independent CB samples. (D) Mitochondrial mass as measured by …

The P2Y1 Receptor Is Necessary for Adenosine 5′-Diphosphate–Induced Platelet Aggregation

…, C Léon, C Vial, P Vigne, C Frelin… - Blood, The Journal …, 1998 - ashpublications.org
… for 15 minutes at 37C and platelet-rich plasma was removed and centrifuged at 1,570g for
15 minutes at 37C. The platelet pellet … Platelets were kept at 37C throughout all experiments. …

[HTML][HTML] Hypoxia up-regulates prolyl hydroxylase activity: a feedback mechansim that limits HIF-1 responses during reoxygenation

…, E Duplan, N Boyer, P Vigne, C Frelin - Journal of Biological …, 2003 - ASBMB
… Reoxygenation Destabilized ODD—To further analyze the effect of reoxygenation, we
generated a chimeric protein consisting of the C-terminal part of the ODD domain of human HIF-1α …

Hypoxia is a strong inducer of vascular endothelial growth factor mRNA expression in the heart

A Ladoux, C Frelin - Biochemical and biophysical research communications, 1993 - Elsevier
… 94C, followed by 35 cycles consisting of 45 s at 92C, 1 min at 54C and 90 s at 72C. Samples
were then treated at 72C for 10 min. RT-PCR products were analysed by electrophoresis …

[PDF][PDF] Intermediate-term hematopoietic stem cells with extended but time-limited reconstitution potential

P Benveniste, C Frelin, S Janmohamed, M Barbara… - Cell stem cell, 2010 - cell.com
… (C) Proportions of 23 mice with unsustained erythroid grafts detectable at 4 or 8 weeks
that also had detectable grafts in the indicated lineages at the time points indicated. ‘‘Proportion …