Fluorinated nucleosides: Synthesis and biological implication
… Chu and coworkers have demonstrated that the enantiomer of FMAU, l-FMAU (Fig. 2), is
a promising agent against HBV [27]. It showed low toxicity in rats and woodchucks, potent in …
a promising agent against HBV [27]. It showed low toxicity in rats and woodchucks, potent in …
Application of bottlebrush block copolymers as photonic crystals
AL Liberman‐Martin, CK Chu… - Macromolecular rapid …, 2017 - Wiley Online Library
Brush block copolymers are a class of comb polymers that feature polymeric side chains
densely grafted to a linear backbone. These polymers display interesting properties due to their …
densely grafted to a linear backbone. These polymers display interesting properties due to their …
l-Nucleosides as chemotherapeutic agents
Nucleoside analogues have been the cornerstone of antiviral therapy over the past thirty
years and, currently, 16 commonly used antiviral drugs belong to this category. Although for …
years and, currently, 16 commonly used antiviral drugs belong to this category. Although for …
Surgical management of hepatic neuroendocrine tumor metastasis: results from an international multi-institutional analysis
…, DA Kooby, CA Staley, JB Stokes, CK Chu… - Annals of surgical …, 2010 - Springer
Background Management of neuroendocrine tumor liver metastasis (NELM) remains
controversial, with some advocating an aggressive surgical approach while others have adopted a …
controversial, with some advocating an aggressive surgical approach while others have adopted a …
Key-aggregate cryptosystem for scalable data sharing in cloud storage
Data sharing is an important functionality in cloud storage. In this paper, we show how to
securely, efficiently, and flexibly share data with others in cloud storage. We describe new public…
securely, efficiently, and flexibly share data with others in cloud storage. We describe new public…
Characterization of human immunodeficiency viruses resistant to oxathiolane-cytosine nucleosides
…, A McMillan, N Ilksoy, CK Chu… - Antimicrobial agents …, 1993 - Am Soc Microbiol
The (-) enantiomers of 2',3'-dideoxy-5-fluoro-3'-thiacytidine [(-)-FTC] and 2',3'-dideoxy-3'-thiacytidine
[(-)-BCH-189] were recently shown to inhibit selectively human immunodeficiency …
[(-)-BCH-189] were recently shown to inhibit selectively human immunodeficiency …
A multicenter analysis of distal pancreatectomy for adenocarcinoma: is laparoscopic resection appropriate?
BACKGROUND: As compared with open distal pancreatectomy (ODP), laparoscopic distal
pancreatectomy (LDP) affords improved perioperative outcomes. The role of LDP for patients …
pancreatectomy (LDP) affords improved perioperative outcomes. The role of LDP for patients …
Kinetic‐theoretic description of the formation of a shock wave
CK Chu - The Physics of Fluids, 1965 - pubs.aip.org
The flow of a gas in a shock tube is treated in the context of kinetic theory as an initial value
problem for the one‐dimensional Krook equation. The only simplifying assumption made is …
problem for the one‐dimensional Krook equation. The only simplifying assumption made is …
A new subtype classification of ischemic stroke based on treatment and etiologic mechanism
SW Han, SH Kim, JY Lee, CK Chu, JH Yang… - European …, 2007 - karger.com
A new subtype classification of ischemic stroke was developed to reflect recent therapeutic
strategies as well as evolving concepts of stroke definitions and mechanisms. In 200 …
strategies as well as evolving concepts of stroke definitions and mechanisms. In 200 …
Epigenetic silencing of HIV-1 by the histone H3 lysine 27 methyltransferase enhancer of Zeste 2
J Friedman, WK Cho, CK Chu, KS Keedy… - Journal of …, 2011 - Am Soc Microbiol
Latent HIV proviruses are silenced as the result of deacetylation and methylation of histones
located at the viral long terminal repeat (LTR). Inhibition of histone deacetylases (HDACs) …
located at the viral long terminal repeat (LTR). Inhibition of histone deacetylases (HDACs) …