Antiemetic efficacy of high-dose metoclopramide: randomized trials with placebo and prochlorperazine in patients with chemotherapy-induced nausea and vomiting
…, LA Bordin, TJ Braun, CW Young - … England Journal of …, 1981 - Mass Medical Soc
In a study of the effectiveness of high intravenous doses of metoclopramide as an antiemetic,
41 patients with advanced cancer who were being treated with cisplatin were entered into …
41 patients with advanced cancer who were being treated with cisplatin were entered into …
[HTML][HTML] … with all-transretinoic acid causes a progressive reduction in plasma drug concentrations: implications for relapse and retinoid “resistance” in patients with …
…, A Jakubowski, DA Scheinberg, CW Young… - Blood, 1992 - Elsevier
Although all-transretinoic acid (RA) induces complete remission in a high proportion of
patients with acute promyelo-cytic leukemia (APL), all groups have described clinical relapses …
patients with acute promyelo-cytic leukemia (APL), all groups have described clinical relapses …
Clinical Pharmacology of Oral All-trans Retinoic Acid in Patients with Acute Promyelocytic Leukemia
…, C Huselton, F DeGrazia, WA Garland, CW Young… - Cancer research, 1992 - AACR
All-trans retinoic acid (RA) induces leukemic cell differentiation and complete remission in a
high proportion of patients with acute promyelocytic leukemia (APL). However, remissions …
high proportion of patients with acute promyelocytic leukemia (APL). However, remissions …
A clinical trial of amygdalin (Laetrile) in the treatment of human cancer
…, G Sarna, R Koch, VE Currie, CW Young… - … England Journal of …, 1982 - Mass Medical Soc
One hundred seventy-eight patients with cancer were treated with amygdalin (Laetrile) plus
a "metabolic therapy" program consisting of diet, enzymes, and vitamins. The great majority …
a "metabolic therapy" program consisting of diet, enzymes, and vitamins. The great majority …
Hydroxyurea: inhibitory effect on DNA metabolism
CW Young, S Hodas - Science, 1964 - science.org
Hydroxyurea, hydroxyurethane, and dihydroxyurea inhibit incorporation of thymidine into the
DNA of monolayers of HeLa cells. They do not affect incorporation of uridine into RNA or of …
DNA of monolayers of HeLa cells. They do not affect incorporation of uridine into RNA or of …
[HTML][HTML] Near-island biological hotspots in barren ocean basins
…, AM Friedlander, JS Ehses, CW Young… - Nature …, 2016 - nature.com
Phytoplankton production drives marine ecosystem trophic-structure and global fisheries
yields. Phytoplankton biomass is particularly influential near coral reef islands and atolls that …
yields. Phytoplankton biomass is particularly influential near coral reef islands and atolls that …
Cisplatin and vindesine combination chemotherapy for advanced carcinoma of the lung: a randomized trial investigating two dosage schedules
…, ME DUKEMAN, N MARTINI, CW YOUNG… - Annals of internal …, 1981 - acpjournals.org
Eighty-five patients with advanced squamous carcinoma or adenocarcinoma of the lung were
randomly assigned to receive vindesine with either high dose (120 mg/m 2 of body surface …
randomly assigned to receive vindesine with either high dose (120 mg/m 2 of body surface …
Butyrate as a differentiating agent: pharmacokinetics, analogues and current status
HL Newmark, JR Lupton, CW Young - Cancer letters, 1994 - Elsevier
The field of butyrate-induced differentiation of neoplastic and non-neoplastic cells is reviewed
and possible clinical correlations considered with regard to butyrate, butyrate prodrugs …
and possible clinical correlations considered with regard to butyrate, butyrate prodrugs …
Prognostic significance of serum lactate dehydrogenase in malignant lymphoma
…, C Little, T Gee, BJ Lee III, V Miké, CW Young - Cancer, 1980 - Wiley Online Library
The pretreatment serum lactate dehydrogenase level (LDH) was the single most important
prognostic variable in 30 patients with diffuse histiocytic lymphoma treated between January …
prognostic variable in 30 patients with diffuse histiocytic lymphoma treated between January …
Treatment of patients with advanced malignant lymphoma using gallium nitrate administered as a seven‐day continuous infusion
RP Warrell Jr, CJ Coonley, DJ Straus, CW Young - Cancer, 1983 - Wiley Online Library
Previous trials of gallium nitrate (NSC‐15200) showed that bolus administration produced
dose‐limiting nephrotoxicity without substantial antitumor activity. As an effort to increase the …
dose‐limiting nephrotoxicity without substantial antitumor activity. As an effort to increase the …