Distribution of metabotropic glutamate receptor mGluR5 immunoreactivity in rat brain

C Romano, MA Sesma, CT McDonald… - Journal of …, 1995 - Wiley Online Library
The receptor mGluR5 is a metabotropic glutamate receptor with messenger RNA abundantly
present throughout cortex, hippocampus, and caudate/putamen that is also coupled to …

[HTML][HTML] Metabotropic glutamate receptor 5 is a disulfide-linked dimer

C Romano, WL Yang, KL O'Malley - Journal of Biological Chemistry, 1996 - ASBMB
The sequences of the metabotropic glutamate receptors (mGluRs) show little homology with
other members of the G protein-coupled receptor family and exhibit several distinctive …

[HTML][HTML] Redox modulation of T-type calcium channels in rat peripheral nociceptors

…, S Mennerick, E Perez-Reyes, C Romano… - Neuron, 2001 - cell.com
Although T-type calcium channels were first described in sensory neurons, their function in
sensory processing remains unclear. In isolated rat sensory neurons, we show that redox …

Selective abolition of the NMDA component of long-term potentiation in mice lacking mGluR5

…, YM Lu, J Henderson, F Taverna, C Romano… - Learning & …, 1998 - learnmem.cshlp.org
The mechanisms underlying the differential expression of long-term potentiation (LTP) by
AMPA and NMDA receptors, are unknown, but could involve G-protein-linked metabotropic …

Modulation of the NMDA receptor by polyamines

K Williams, C Romano, MA Dichter, PB Molinoff - Life sciences, 1991 - Elsevier
Results of recent biochemical and electrophysiological studies have suggested that a
recognition site for polyamines exists as part of the NMDA receptor complex. This site appears to …

Localization of mGluR1a-like immunoreactivity and mGluR5-like immunoreactivity in identified populations of striatal neurons

SJ Tallaksen-Greene, KW Kaatz, C Romano, RL Albin - Brain research, 1998 - Elsevier
Metabotropic glutamate receptors are important mediators of excitatory amino acid
neurotransmission in the striatum. Two-color immunofluorescence histochemistry and …

Anti-Ro/SS-A positivity and heat shock protein antibodies in patients with normal-pressure glaucoma

…, I Saito, RS Gupta, JB Harley, Z Li, C Romano - American journal of …, 1998 - Elsevier
PURPOSE: To describe the clinical and laboratory findings in 10 patients with normal-pressure
glaucoma and anti-Ro/SS-A positivity by enzymelinked immunosorbent assay (ELISA) …

[HTML][HTML] Serum autoantibody against glutathione S-transferase in patients with glaucoma

J Yang, G Tezel, RV Patil, C Romano… - … ophthalmology & visual …, 2001 - arvojournals.org
purpose. To identify retinal proteins that are the targets of serum autoantibodies in patients
with glaucoma. methods. To identify retinal antigens that are recognized by the sera of …

Enhanced early developmental expression of the metabotropic glutamate receptor mGluR5 in rat brain: protein, mRNA splice variants, and regional distribution

C Romano, AN Van den Pol… - Journal of Comparative …, 1996 - Wiley Online Library
Glutamate stimulates phosphatidyl inositol hydrolysis and mobilizes intracellular calcium
through the mediation of metabotropic glutamate receptors (mGluRs), in particular the “Group I” …

[HTML][HTML] Activation of metabotropic glutamate receptor mGlu5 on nuclear membranes mediates intranuclear Ca2+ changes in heterologous cell types and neurons

…, YJI Jong, Y Gonchar, A Burkhalter, C Romano - Journal of Biological …, 2003 - ASBMB
Nuclear Ca 2 + plays a critical role in many cellular functions although its mode (s) of regulation
is unclear. This study shows that the metabotropic glutamate receptor, mGlu5, mobilizes …