[PDF][PDF] Small molecule inhibition of the autophagy kinase ULK1 and identification of ULK1 substrates
…, CJ Miller, HJ Lou, D Raveendra-Panickar, CC Yang… - Molecular cell, 2015 - cell.com
Many tumors become addicted to autophagy for survival, suggesting inhibition of autophagy
as a potential broadly applicable cancer therapy. ULK1/Atg1 is the only serine/threonine …
as a potential broadly applicable cancer therapy. ULK1/Atg1 is the only serine/threonine …
[PDF][PDF] MDA5 governs the innate immune response to SARS-CoV-2 in lung epithelial cells
Recent studies have profiled the innate immune signatures in patients infected with severe
acute respiratory syndrome coronavirus 2 (SARS-CoV-2) and suggest that cellular responses …
acute respiratory syndrome coronavirus 2 (SARS-CoV-2) and suggest that cellular responses …
Thiazolidenediones mediate apoptosis in prostate cancer cells in part through inhibition of Bcl-xL/Bcl-2 functions independently of PPARγ
CW Shiau, CC Yang, SK Kulp, KF Chen, CS Chen… - Cancer research, 2005 - AACR
Certain members of the thiazolidenedione family of the peroxisome proliferator-activated
receptor γ (PPARγ) agonists, such as troglitazone and ciglitazone, exhibit antitumor effects; …
receptor γ (PPARγ) agonists, such as troglitazone and ciglitazone, exhibit antitumor effects; …
Histone deacetylase inhibitors sensitize prostate cancer cells to agents that produce DNA double-strand breaks by targeting Ku70 acetylation
…, YC Wang, HC Yang, PH Huang, SK Kulp, CC Yang… - Cancer research, 2007 - AACR
This study reports a histone deacetylation-independent mechanism whereby histone
deacetylase (HDAC) inhibitors sensitize prostate cancer cells to DNA-damaging agents by …
deacetylase (HDAC) inhibitors sensitize prostate cancer cells to DNA-damaging agents by …
Effect of surface roughness of tool electrode materials in ECDM performance
CK Yang, CP Cheng, CC Mai, AC Wang… - International Journal of …, 2010 - Elsevier
Electrochemical discharge machining (ECDM) is an emerging non-traditional machining
process that involves high-temperature melting assisted by accelerated chemical etching. In …
process that involves high-temperature melting assisted by accelerated chemical etching. In …
Study of gas film quality in electrochemical discharge machining
CP Cheng, KL Wu, CC Mai, CK Yang, YS Hsu… - International Journal of …, 2010 - Elsevier
Electrochemical Discharge Machining (ECDM) has been demonstrated to be an alternative
spark-based micromachining method for fabricating microholes and microchannels in non-…
spark-based micromachining method for fabricating microholes and microchannels in non-…
[PDF][PDF] A network of conserved synthetic lethal interactions for exploration of precision cancer therapy
An emerging therapeutic strategy for cancer is to induce selective lethality in a tumor by
exploiting interactions between its driving mutations and specific drug targets. Here we use a …
exploiting interactions between its driving mutations and specific drug targets. Here we use a …
SARS-CoV-2 ORF9c is a membrane-associated protein that suppresses antiviral responses in cells
Disrupted antiviral immune responses are associated with severe COVID-19, the disease
caused by SAR-CoV-2. Here, we show that the 73-amino-acid protein encoded by ORF9c of …
caused by SAR-CoV-2. Here, we show that the 73-amino-acid protein encoded by ORF9c of …
[HTML][HTML] α-Tocopheryl succinate induces apoptosis in prostate cancer cells in part through inhibition of Bcl-xL/Bcl-2 function
…, JW Huang, DS Wang, JR Weng, CC Yang… - Journal of Biological …, 2006 - ASBMB
Although the antitumor effect of α-tocopheryl succinate (vitamin E succinate) has been well
demonstrated, its underlying mechanism remains elusive. This study provides evidence that …
demonstrated, its underlying mechanism remains elusive. This study provides evidence that …
Paleoseismic events and recurrence interval along the Beichuan–Yingxiu fault of Longmenshan fault zone, Yingxiu, Sichuan, China
Prior to the 2008 Wenchuan earthquake (Mw 7.9), Sichuan, China, no earthquake of magnitude
larger than M 7.0 had been reported in the historical record for the Longmenshan region…
larger than M 7.0 had been reported in the historical record for the Longmenshan region…