Methods Data bases from the Surveillance, Epidemiology and End Results (SEER) program
of the National Cancer Institute and the International Agency for Research on Cancer (IARC)…

Background Prostate-specific membrane antigen (PSMA) is upregulated in androgen-dependent
prostate carcinoma and it has been targeted for immunotherapy and diagnosis of this …

(–)-Epigallocatechin-3-gallate (EGCG) is the major polyphenol present in green tea. We
previously demonstrated that EGCG was both a substrate and potent inhibitor of human liver …

The mutagenic activity of a group of diazo dyes based on benzidine and its congeners was
compared following metabolic activation of the dyes through sequential reduction and …

Ulcerative colitis is inflammatory conditions of the colon caused by interplay of genetic and
environmental factors. Previous studies indicated that the gut microflora may be involved in …

Purpose : In this study we evaluated the risk of a second malignancy of the bladder or prostate
in patients with a previous diagnosis of prostate cancer (PCa) or urothelial cancer (TCC). …

A number of studies report a high frequency of double primary cancers of the bladder and
prostate. The coincidence was as high as 70% for prostate cancers in patients with bladder …

Nitropyrene, a direct-acting mutagenic component of extracts of diesel exhaust and ambient
air particulates, is one of the major nitroarenes found in products of incomplete combustion. …

Purpose : Recent guidelines recommend that men older than 75 years should not be
screened for prostate cancer. However, increased life expectancy and the development of less …

In order to study the mutagenic effects of heterocyclic aromatic amines (HAAs) in cells of
human origin, five compounds, namely 2-amino-3-methyl-imidazo[4,5-f]quinoline (IQ), 2-amino-3…