Identification of molecular targets of the oligomeric nonprenylated acylphloroglucinols from Myrtus communis and their implication as anti-inflammatory compounds
C Feißt, L Franke, G Appendino, O Werz - Journal of Pharmacology and …, 2005 - ASPET
Myrtucommulone (MC) and semimyrtucommulone (S-MC) are unique oligomeric, nonprenylated
acylphloroglucinols contained in the leaves of myrtle (Myrtus communis). Although …
acylphloroglucinols contained in the leaves of myrtle (Myrtus communis). Although …
Hyperforin is a novel type of 5-lipoxygenase inhibitor with high efficacy in vivo
C Feißt, C Pergola, M Rakonjac, A Rossi… - Cellular and molecular …, 2009 - Springer
We previously showed that, in vitro, hyperforin from St. John’s wort (Hypericum perforatum)
inhibits 5-lipoxygenase (5-LO), the key enzyme in leukotriene biosynthesis. Here, we …
inhibits 5-lipoxygenase (5-LO), the key enzyme in leukotriene biosynthesis. Here, we …
Suppression of receptor-mediated Ca2+ mobilization and functional leukocyte responses by hyperforin
C Feisst, O Werz - Biochemical pharmacology, 2004 - Elsevier
We have recently identified hyperforin, a lipophilic constituent of the herb Hypericum perforatum
(St. John’s wort), as a dual inhibitor of the proinflammatory enzymes cyclooxygenase-1 …
(St. John’s wort), as a dual inhibitor of the proinflammatory enzymes cyclooxygenase-1 …
Induction of central signalling pathways and select functional effects in human platelets by β‐boswellic acid
D Poeckel, L Tausch, A Altmann, C Feißt… - British journal of …, 2005 - Wiley Online Library
We have recently shown that in polymorphonuclear leukocytes, 11‐keto boswellic acids (KBAs)
induce Ca 2+ mobilisation and activation of mitogen‐activated protein kinases (MAPK). …
induce Ca 2+ mobilisation and activation of mitogen‐activated protein kinases (MAPK). …
The aminosteroid phospholipase C antagonist U-73122 (1-[6-[[17-β-3-methoxyestra-1, 3, 5 (10)-trien-17-yl] amino] hexyl]-1H-pyrrole-2, 5-dione) potently inhibits …
C Feißt, D Albert, D Steinhilber, O Werz - Molecular pharmacology, 2005 - ASPET
… Christian Feißt, Dana Albert, Dieter Steinhilber and Oliver Werz … In agreement with others
(Bleasdale et al., 1990; Smith et al., 1990; Hou et al., 2004) and with our recent report (Feisst …
(Bleasdale et al., 1990; Smith et al., 1990; Hou et al., 2004) and with our recent report (Feisst …
Hyperforin induces Ca2+-independent arachidonic acid release in human platelets by facilitating cytosolic phospholipase A2 activation through select phospholipid …
M Hoffmann, JJ Lopez, C Pergola, C Feisst… - … et Biophysica Acta (BBA …, 2010 - Elsevier
Here, we investigated the modulation of cytosolic phospholipase A 2 (cPLA 2 )-mediated
arachidonic acid (AA) release by the polyprenylated acylphloroglucinol hyperforin. Hyperforin …
arachidonic acid (AA) release by the polyprenylated acylphloroglucinol hyperforin. Hyperforin …
Evaluation of hyperforin analogues for inhibition of 5-lipoxygenase
The acylphloroglucinol hyperforin, a constituent of the herb Hypericum perforatum (St. John's
wort), was recently identified as potent and direct inhibitor of 5-lipoxygenase (5-LO), the …
wort), was recently identified as potent and direct inhibitor of 5-lipoxygenase (5-LO), the …
On the molecular basis of novel anti-inflammatory compounds and functional leukocyte responses
C Feißt - 2006 - publikationen.ub.uni-frankfurt.de
Inflammation is a complex pathophysiological event that can be triggered by activation of a
number of distinct activation pathways eventually leading to the release of pro-inflammatory …
number of distinct activation pathways eventually leading to the release of pro-inflammatory …
[CITATION][C] The aminosteroid phospholipase C antagonist U-73122 potently inhibits human 5-lipoxygenase in vivo and in vitro
C Feisst, D Albert, D Steinhilber, O Werz - Molecular Pharmacology, 2005 - ASPET
The aminosteroid U-73122(1-[6-[[17-beta-3-methoxyestra-1, 3, 5 (10)-trien-17-yl] amino]
hexyl]-1H-pyrrole-2, 5-dione) is widely used as a tool to investigate the involvement of the …
hexyl]-1H-pyrrole-2, 5-dione) is widely used as a tool to investigate the involvement of the …
System Architecture for Device and Content Independent Communication Including 3D Imaging
R Sultana, A Christ, P Meyrueis - QScience Proceedings, 2013 - qscience.com
… and device dependent content (Christ & Feisst 2010). This idea is implemented in a
helping tool for language acquisition for adult learners named Language Learning Game (LLG). …
helping tool for language acquisition for adult learners named Language Learning Game (LLG). …