[3H] RY 80: A High-Affinity, Selective Ligand for γ-Aminobutyric AcidA Receptors ContainingAlpha-5 Subunits
P Skolnick, RJ Hu, CM Cook, SD Hurt… - … of Pharmacology and …, 1997 - ASPET
The radiochemical synthesis and pharmacological properties are described of [ 3 H]RY 80 (ethyl-8-acetylene-5,6-dihydro-5-methyl-6-oxo-4H-imidazo[1,5a][1,4]benzodiazepine-3-…
[HTML][HTML] HIV and Drug Use: A Tale of Synergy in Pulmonary Vascular Disease Development
CM Cook, VD Craddock, AK Ram… - Comprehensive …, 2023 - ncbi.nlm.nih.gov
Over the past two decades, with the advent and adoption of highly active anti-retroviral
therapy, HIV-1 infection, a once fatal and acute illness, has transformed into a chronic disease …
therapy, HIV-1 infection, a once fatal and acute illness, has transformed into a chronic disease …
The pursuit of noninvasive diagnosis of lung cancer
T Atwater, CM Cook, PP Massion - Seminars in respiratory and …, 2016 - thieme-connect.com
The noninvasive diagnosis of lung cancer remains a formidable challenge. Although tissue
diagnosis will remain the gold standard for the foreseeable future, questions pertaining to the …
diagnosis will remain the gold standard for the foreseeable future, questions pertaining to the …
[HTML][HTML] Incomplete home health care referral after hospitalization among Medicare beneficiaries
…, CM Cook, D Pierotti, M Steele-Adjognon… - Journal of the American …, 2021 - Elsevier
Objectives Patients who are referred to home health care after an acute care hospitalization
may not receive home health care, resulting in incomplete home health referrals. This study …
may not receive home health care, resulting in incomplete home health referrals. This study …
Excipient-induced pulmonary vascular disease: an underrecognized and deadly complication of opioid addiction
CM Cook, SQ Simpson, L Satterwhite - Lung, 2021 - Springer
Despite widespread public health concern regarding opioid misuse and overuse, there is a
paucity of literature on the acute and chronic pulmonary vascular and cardiac implications of …
paucity of literature on the acute and chronic pulmonary vascular and cardiac implications of …
A single amino acid residue on the α5 subunit (Ile215) is essential for ligand selectivity at α5β3γ2 γ-aminobutyric acidA receptors
MI Strakhova, SC Harvey, CM Cook, JM Cook… - Molecular …, 2000 - ASPET
Imidazobenzodiazepines such as RY-80 have been reported to exhibit both high affinity and
selectivity for GABA A receptors containing an α 5 subunit. A single amino acid residue (α 5 …
selectivity for GABA A receptors containing an α 5 subunit. A single amino acid residue (α 5 …
[HTML][HTML] Exploring extracellular vesicles as mediators of clinical disease and vehicles for viral therapeutics: Insights from the COVID-19 pandemic
VD Craddock, CM Cook, NK Dhillon - Extracellular vesicles and …, 2022 - ncbi.nlm.nih.gov
The COVID-19 pandemic has challenged researchers to rapidly understand the capabilities
of the SARS-CoV-2 virus and investigate potential therapeutics for SARS-CoV-2 infection. …
of the SARS-CoV-2 virus and investigate potential therapeutics for SARS-CoV-2 infection. …
[HTML][HTML] A review of the modern, multidisciplinary approach to the management of massive hemoptysis
CM Cook, MP Jasahui - Shanghai Chest, 2020 - shc.amegroups.org
Massive hemoptysis was once considered a surgical emergency necessitating thoracotomy.
Fortunately, technology has evolved to facilitate rapid localization and control of bleeding …
Fortunately, technology has evolved to facilitate rapid localization and control of bleeding …
[PDF][PDF] Characterization of large structural genetic mosaicism in human autosomes
Analyses of genome-wide association study (GWAS) data have revealed that detectable
genetic mosaicism involving large (>2 Mb) structural autosomal alterations occurs in a fraction …
genetic mosaicism involving large (>2 Mb) structural autosomal alterations occurs in a fraction …
Evidence of novel susceptibility variants for prostate cancer and a multiancestry polygenic risk score associated with aggressive disease in men of African ancestry
…, MC Stern, Z Kote-Jarai, K Govindasami, MB Cook… - European urology, 2023 - Elsevier
Background Genetic factors play an important role in prostate cancer (PCa) susceptibility.
Objective To discover common genetic variants contributing to the risk of PCa in men of African …
Objective To discover common genetic variants contributing to the risk of PCa in men of African …