User profiles for Daniel T. O’Connor

Daniel T. O'Connor

University of California at San Diego
Verified email at ucsd.edu
Cited by 26857

The chromogranin–secretogranin family

…, KL Harper, DT O'Connor - New England Journal of …, 2003 - Mass Medical Soc
The members of the chromogranin–secretogranin family of peptide hormones, biogenic amines,
and neurotransmitters are enclosed within vesicles in the neuroendocrine system and a …

Secretion of chromogranin A by peptide-producing endocrine neoplasms

DT O'Connor, LJ Deftos - New England Journal of Medicine, 1986 - Mass Medical Soc
Chromogranin A, the protein that is co-stored and co-released with catecholamines from the
adrenal medulla, has recently been identified in a variety of human endocrine tissues, both …

Novel autocrine feedback control of catecholamine release. A discrete chromogranin a fragment is a noncompetitive nicotinic cholinergic antagonist.

SK Mahata, DT O'Connor, M Mahata… - The Journal of …, 1997 - Am Soc Clin Investig
Catecholamine secretory vesicle core proteins (chromogranins) contain an activity that inhibits
catecholamine release, but the identity of the responsible peptide has been elusive. Size-…

Plasma hydrogen peroxide production in hypertensives and normotensive subjects at genetic risk of hypertension

F Lacy, DT O'Connor… - Journal of …, 1998 - journals.lww.com
… To determine whether inhibition of SOD could be a source of error when measuring
concentrations of hydrogen peroxide in plasma samples, we measured H 2 O 2 …

Assessment of plasma C-reactive protein as a biomarker of posttraumatic stress disorder risk

…, N Biswas, A Agorastos, DT O'Connor… - JAMA …, 2014 - jamanetwork.com
Importance Posttraumatic stress disorder (PTSD) has been associated in cross-sectional
studies with peripheral inflammation. It is not known whether this observed association is the …

Plasma hydrogen peroxide production in human essential hypertension: role of heredity, gender, and ethnicity

F Lacy, MT Kailasam, DT O'Connor… - …, 2000 - Am Heart Assoc
Oxygen free radicals, including hydrogen peroxide, may mediate oxidative stress in target
organ tissues and contribute to cardiovascular complications in hypertension. To examine …

[HTML][HTML] Genetic influences on endometriosis in an Australian twin sample

SA Treloar, DT O'Connor, VM O'Connor, NG Martin - Fertility and sterility, 1999 - Elsevier
Objective: To investigate the prevalence of and twin pair concordance for endometriosis.
Design: A questionnaire survey incorporating validation. Setting: An Australia-wide volunteer …

[HTML][HTML] Hypertension from targeted ablation of chromogranin A can be rescued by the human ortholog

NR Mahapatra, DT O'Connor… - The Journal of …, 2005 - Am Soc Clin Investig
The secretory prohormone chromogranin A (CHGA) is overexpressed in essential
hypertension, a complex trait with genetic predisposition, while its catecholamine release–inhibitory …

[PDF][PDF] Genomewide linkage study in 1,176 affected sister pair families identifies a significant susceptibility locus for endometriosis on chromosome 10q26

…, KR Ewen-White, DL Duffy, DT O'Connor… - The American Journal of …, 2005 - cell.com
Endometriosis is a common gynecological disease that affects up to 10% of women in their
reproductive years. It causes pelvic pain, severe dysmenorrhea, and subfertility. The disease …

[HTML][HTML] Whole-genome analysis of sporadic amyotrophic lateral sclerosis

…, J Rosenfeld, DT O'Connor… - New England journal …, 2007 - Mass Medical Soc
Background Approximately 90% of persons with amyotrophic lateral sclerosis (ALS) have
the sporadic form, which may be caused by the interaction of multiple environmental factors …