[BOOK][B] Praxial music education: Reflections and dialogues

DJ Elliot - 2009 - books.google.com
Praxial Music Education is a collection of essays by nineteen internationally recognized
scholars in music education. Each essay offers critical reflections on a key topic in contemporary …

Selectivity of substrate (trifluoperazine) and inhibitor (amitriptyline, androsterone, canrenoic acid, hecogenin, phenylbutazone, quinidine, quinine, and sulfinpyrazone)“ …

V Uchaipichat, PI Mackenzie, DJ Elliot… - Drug metabolism and …, 2006 - ASPET
Relatively few selective substrate and inhibitor probes have been identified for human UDP-glucuronosyltransferases
(UGTs). This work investigated the selectivity of trifluoperazine (…

In vitro characterization of lamotrigine N2-glucuronidation and the lamotrigine-valproic acid interaction

A Rowland, DJ Elliot, JA Williams, PI Mackenzie… - Drug Metabolism and …, 2006 - ASPET
Studies were performed to investigate the UDP-glucuronosyltransferase enzyme(s)
responsible for the human liver microsomal N2-glucuronidation of the anticonvulsant drug …

Quantitative prediction of in vivo inhibitory interactions involving glucuronidated drugs from in vitro data: the effect of fluconazole on zidovudine glucuronidation

…, LK Winner, PI Mackenzie, DJ Elliot… - British journal of …, 2006 - Wiley Online Library
Aims Using the fluconazole–zidovudine (AZT) interaction as a model, to determine whether
inhibition of UDP–glucuronosyltransferase (UGT) catalysed drug metabolism in vivo could …

Binding of inhibitory fatty acids is responsible for the enhancement of UDP-glucuronosyltransferase 2B7 activity by albumin: implications for in vitro-in vivo …

A Rowland, P Gaganis, DJ Elliot, PI Mackenzie… - … of Pharmacology and …, 2007 - ASPET
Studies were performed to elucidate the mechanism responsible for the reduction in K m
values of UDP-glucuronosyltransferase 2B7 (UGT2B7) substrates observed for incubations …

Influence of mutations associated with Gilbert and Crigler–Najjar type II syndromes on the glucuronidation kinetics of bilirubin and other UDP-glucuronosyltransferase …

W Udomuksorn, DJ Elliot, BC Lewis… - Pharmacogenetics …, 2007 - journals.lww.com
Objectives UGT1A1 coding region mutations, including UGT1A1* 6 (G71R), UGT1A1* 7 (Y486D),
UGT1A1* 27 (P229Q) and UGT1A1* 62 (F83L), have been linked to Gilbert syndrome …

Characterization of niflumic acid as a selective inhibitor of human liver microsomal UDP-glucuronosyltransferase 1A9: application to the reaction phenotyping of …

JO Miners, K Bowalgaha, DJ Elliot… - Drug Metabolism and …, 2011 - ASPET
Enzyme selective inhibitors represent the most valuable experimental tool for reaction
phenotyping. However, only a limited number of UDP-glucuronosyltransferase (UGT) enzyme-…

The novel UDP glycosyltransferase 3A2: cloning, catalytic properties, and tissue distribution

PI MacKenzie, A Rogers, DJ Elliot, N Chau… - Molecular …, 2011 - ASPET
The human UDP glycosyltransferase (UGT) 3A family is one of three families involved in the
metabolism of small lipophilic compounds. Members of these families catalyze the addition …

S‐Naproxen and desmethylnaproxen glucuronidation by human liver microsomes and recombinant human UDP‐glucuronosyltransferases (UGT): role of UGT2B7 in …

K Bowalgaha, DJ Elliot, PI Mackenzie… - British journal of …, 2005 - Wiley Online Library
Aims To characterize the kinetics of S‐naproxen (‘naproxen’) acyl glucuronidation and
desmethylnaproxen acyl and phenolic glucuronidation by human liver microsomes and identify …

The “albumin effect” and in vitro-in vivo extrapolation: sequestration of long-chain unsaturated fatty acids enhances phenytoin hydroxylation by human liver …

A Rowland, DJ Elliot, KM Knights, PI Mackenzie… - Drug metabolism and …, 2008 - ASPET
This study characterized the mechanism by which bovine serum albumin (BSA) reduces the
K m for phenytoin (PHY) hydroxylation and the implications of the “albumin effect” for in vitro-…