[HTML][HTML] Attenuation of the activity of the cAMP-specific phosphodiesterase PDE4A5 by interaction with the immunophilin XAP2
…, C MacKenzie, DG McEwan, DA Wallace… - Journal of Biological …, 2003 - ASBMB
The cyclic AMP-specific phosphodiesterase (PDE4) isoform PDE4A5 interacted with the
immunophilin XAP2 in a yeast two-hybrid assay. The interaction was confirmed in biochemical …
immunophilin XAP2 in a yeast two-hybrid assay. The interaction was confirmed in biochemical …
p75 neurotrophin receptor regulates tissue fibrosis through inhibition of plasminogen activation via a PDE4/cAMP/PKA pathway
…, MA Passino, C Schachtrup, DA Wallace… - The Journal of cell …, 2007 - rupress.org
Clearance of fibrin through proteolytic degradation is a critical step of matrix remodeling that
contributes to tissue repair in a variety of pathological conditions, such as stroke, …
contributes to tissue repair in a variety of pathological conditions, such as stroke, …
Phosphorylation of cAMP-specific PDE4A5 (phosphodiesterase-4A5) by MK2 (MAPKAPK2) attenuates its activation through protein kinase A phosphorylation
KF MacKenzie, DA Wallace, EV Hill… - Biochemical …, 2011 - portlandpress.com
cAMP-specific PDE (phosphodiesterase) 4 isoforms underpin compartmentalized cAMP
signalling in mammalian cells through targeting to specific signalling complexes. Their …
signalling in mammalian cells through targeting to specific signalling complexes. Their …
The role of indirect photolysis in limiting the persistence of crop protection products in surface waters
DF Wallace, LH Hand, RG Oliver - … Toxicology and Chemistry …, 2010 - Wiley Online Library
The photodegradation of six crop protection products (CPPs) was studied in 16 natural
waters collected from across the midwest of the United States under simulated sunlight to …
waters collected from across the midwest of the United States under simulated sunlight to …
Identification and characterization of PDE4A11, a novel, widely expressed long isoform encoded by the human PDE4A cAMP phosphodiesterase gene
DA Wallace, LA Johnston, E Huston, D MacMaster… - Molecular …, 2005 - ASPET
PDE4A11 is a novel cAMP-specific phosphodiesterase that is conserved in humans, mouse,
rat, pig, and bat. Exon-1 4A11 encodes its unique, 81 amino acid N-terminal region. …
rat, pig, and bat. Exon-1 4A11 encodes its unique, 81 amino acid N-terminal region. …
Pyrfume: A Window to the World's Olfactory Data
…, Z Liang, LA Coleman, F Patel, DS Wallace… - bioRxiv, 2022 - biorxiv.org
Advances in theoretical understanding are frequently unlocked by access to large, diverse
experimental datasets. Olfactory neuroscience and psychophysics remain years behind the …
experimental datasets. Olfactory neuroscience and psychophysics remain years behind the …
Heat flow and depth versus age for the Mesozoic northwest Atlantic Ocean: results from the Sohm abyssal plain and implications for the Bermuda Rise
KE Louden, DO Wallace, RC Courtney - Earth and planetary science letters, 1987 - Elsevier
Heat flow in the Sohm abyssal plain is measured to be 53 mW/m 2 at an age of 163 Ma.
This is 25% higher than predicted by conductive cooling models, even though the sediment-…
This is 25% higher than predicted by conductive cooling models, even though the sediment-…
Protective efficacy of the recombinant, live-attenuated, CYD tetravalent dengue vaccine in Thai schoolchildren: a randomised, controlled phase 2b trial
A Sabchareon, D Wallace, C Sirivichayakul… - The Lancet, 2012 - thelancet.com
Background Roughly half the world's population live in dengue-endemic countries, but no
vaccine is licensed. We investigated the efficacy of a recombinant, live, attenuated tetravalent …
vaccine is licensed. We investigated the efficacy of a recombinant, live, attenuated tetravalent …
[HTML][HTML] Efficacy of a tetravalent dengue vaccine in healthy children and adolescents
…, S Bizjajeva, L Bravo, D Wallace - … England Journal of …, 2019 - Mass Medical Soc
Background Dengue, a mosquito-borne viral disease, was designated a World Health
Organization top 10 threat to global health in 2019. Methods We present primary efficacy data …
Organization top 10 threat to global health in 2019. Methods We present primary efficacy data …
Three-year efficacy and safety of Takeda's dengue vaccine candidate (TAK-003)
…, I LeFevre, V Tricou, D Wallace… - Clinical Infectious …, 2022 - academic.oup.com
Background Takeda’s live attenuated tetravalent dengue vaccine candidate (TAK-003) is
under evaluation in a long-term clinical trial across 8 dengue-endemic countries. Previously, …
under evaluation in a long-term clinical trial across 8 dengue-endemic countries. Previously, …