We have conducted a genome screen of autism, by linkage analysis in an initial set of 90
multiplex sibships, with parents, containing 97 independent affected sib pairs (ASPs), with …

In vivo, supraphysiological doses of glucocorticoids are required to restore adrenal
medullary phenylethanolamine N‐methyltransferase (PNMT, EC 2.1.1.28) activity after …

Two newly identified, overlapping (1 bp) glucocorticoid response elements (GREs) at −759
and −773 bp in the promoter of the rat phenylethanolamine N-methyltransferase (PNMT; EC …

The adrenal gland is the body's primary source for epinephrine production and release, and
the chromaffin cells that comprise the adrenal medulla possess all of the catecholamine …

Stress effects on adrenergic responses in rats were examined in adrenal medulla, the
primary source of circulating epinephrine (Epi). Irrespective of duration, immobilization (IMMO) …

The gene encoding the epinephrine synthesizing enzyme, phenylethanolamine N-methyltransferase
(PNMT), is transcriptionally activated by Egr-1, AP-2, and the glucocorticoid …

The immediate early gene transcription factor Egr-1 increases luciferase reporter gene
activity 3-4-fold when a rat phenylethanolamine N-methyltransferase (PNMT) promoter-luciferase …

Phenylethanolamine N-methyltransferase (PNMT), the final enzyme in the pathway for
epinephrine biosynthesis, serves as a marker for tissues and cells producing epinephrine. The …

Immobilization (IMMO) stress was used to examine how stress alters the stress hormone
epinephrine (EPI) in the adrenal medulla in vivo. In rats subjected to IMMO for 30 or 120 min, …

The rat phenylethanolamine N-methyltransferase (PNMT) gene promoter contains 1-base
pair (bp) overlapping consensus sequences for Sp1 and MAZ transcription factors at -48 and -…