Bee venom (BV) therapy (BVT), the therapeutic application of BV, has been used in traditional
medicine to treat diseases, such as arthritis, rheumatism, pain, cancerous tumors, and skin …

Interleukin-32 (IL-32) is a novel cytokine involved in inflammation and cancer development.
IL-32 gene consists of eight small exons, and IL-32 mRNA has nine alternative spliced …

Objective To investigate the molecular mechanisms of the antiarthritic effects of bee venom (BV)
and melittin (a major component of BV) in a murine macrophage cell line (Raw 264.7) …

MicroRNAs (miRNAs) regulate cardiovascular biology and disease, but the role of flow-sensitive
microRNAs in atherosclerosis is still unclear. Here we identify miRNA-712 (miR-712) as …

In atherosclerosis, plaques preferentially develop in arterial regions of disturbed blood flow (d-flow),
which alters endothelial gene expression and function. Here, we determined that d-…

Cinnamomum cassia has been widely used for treating dyspepsia, gastritis, and inflammatory
disease. In the present study, several of cinnamaldehyde derivatives were synthesized …

The current study presents an effective and selective multifunctional nanoparticle used to
deliver antiatherogenic therapeutics to inflamed pro-atherogenic regions without off-target …

Recently, we showed that disturbed flow caused by a partial ligation of mouse carotid artery
rapidly induces atherosclerosis. Here, we identified mechanosensitive genes in vivo through …

Neuroinflammation is significant in the pathogenesis and development of Alzheimer's
disease (AD). Previously, we showed lipopolysaccharide (LPS)-induced neuroinflammation …

Background Bee venom therapy has been used to treat inflammatory diseases including
rheumatoid arthritis in humans and in experimental animals. We previously found that bee …