Many antibiotics, chemotherapeutics, crop protection agents and food preservatives originate
from molecules produced by bacteria, fungi or plants. In recent years, genome mining …

Covering: up to June 2020 Ribosomally-synthesized and post-translationally modified
peptides (RiPPs) are a large group of natural products. A community-driven review in 2013 …

Covering: 1988 to 2012 This review presents recommended nomenclature for the biosynthesis
of ribosomally synthesized and post-translationally modified peptides (RiPPs), a rapidly …

Ribosomally synthesized and post-translationally modified peptides (RiPPs) are a natural
product class that has undergone significant expansion due to the rapid growth in genome …

Nitric oxide (NO) signaling through the formation of cGMP is well established; however,
there seems to be an increasing role for cGMP-independent NO signaling. Although key …

A wide variety of enzymatic pathways that produce specialized metabolites in bacteria, fungi
and plants are known to be encoded in biosynthetic gene clusters. Information about these …

We report the discovery of a series of new drug leads that have potent activity against
Mycobacterium tuberculosis as well as against other bacteria, fungi, and a malaria parasite. The …

Exceptionally high peroxidase-like and catalase-like activities of iron(III)−TAML activators of
H 2 O 2 ( 1: Tetra-Amidato-Macrocyclic-Ligand Fe III complexes [ F e{1,2−X 2 C 6 H 2 −4,5−( …

Oxidation of Orange II ([4-[(2-hydroxynaphtyl)azo]benzenesulfonic acid], sodium salt) by
hydrogen peroxide catalyzed by iron(III) complexed to tetra amido macrocyclic ligands (FeIII–…

With billions of years of evolution under its belt, Nature has been expanding and optimizing
its biosynthetic capabilities. Chemically complex secondary metabolites continue to …