User profiles for Duo Lu

Duo Lu

Rider University
Verified email at rider.edu
Cited by 476

[HTML][HTML] The Ikaros family of zinc-finger proteins

Y Fan, D Lu - Acta Pharmaceutica Sinica B, 2016 - Elsevier
Ikaros represents a zinc-finger protein family important for lymphocyte development and
certain other physiological processes. The number of family members is large, with alternative …

Crystal structure of a zinc-finger–RNA complex reveals two modes of molecular recognition

D Lu, M Alexandra Searles, A Klug - Nature, 2003 - nature.com
Zinc-finger proteins of the classical Cys 2 His 2 type are the most frequently used class of
transcription factor and account for about 3% of genes in the human genome 1 , 2 . The zinc-…

[HTML][HTML] An appraisal of lung nodules automatic classification algorithms for CT images

X Wang, K Mao, L Wang, P Yang, D Lu, P He - Sensors, 2019 - mdpi.com
Lung cancer is one of the most deadly diseases around the world representing about 26%
of all cancers in 2017. The five-year cure rate is only 18% despite great progress in recent …

Drug resistance confounding prion therapeutics

DB Berry, D Lu, M Geva, JC Watts… - Proceedings of the …, 2013 - National Acad Sciences
There is not a single pharmaceutical that halts or even slows any neurodegenerative disease.
Mounting evidence shows that prions cause many neurodegenerative diseases, and …

Effects of Chondroitinase ABC and Chymopapain on Spinal Motion Segment Biomechanics: An: In Vivo: Biomechanical, Radiologic, and Histologic Canine Study

DS Lü, Y Shono, I Oda, K Abumi, K Kaneda - Spine, 1997 - journals.lww.com
Study Design. The biomechanical effects of chondroitinase ABC and chymopapain related
to spinal segmental instability were investigated using a canine model, as well by as …

Structural basis of Escherichia coli single-stranded DNA-binding protein stimulation of exonuclease I

D Lu, JL Keck - Proceedings of the National Academy of …, 2008 - National Acad Sciences
Bacterial single-stranded DNA (ssDNA)-binding proteins (SSBs) play essential protective
roles in genome biology by shielding ssDNA from damage and preventing spurious DNA …

A secure microservice framework for iot

D Lu, D Huang, A Walenstein… - 2017 IEEE Symposium …, 2017 - ieeexplore.ieee.org
The Internet of Things (IoT) has connected an incredible diversity of devices in novel ways,
which has enabled exciting new services and opportunities. Unfortunately, IoT systems also …

Structure-based mechanism of lipoteichoic acid synthesis by Staphylococcus aureus LtaS

D Lu, ME Wörmann, X Zhang… - Proceedings of the …, 2009 - National Acad Sciences
Staphylococcus aureus synthesizes polyglycerol-phosphate lipoteichoic acid (LTA) from
phosphatidylglycerol. LtaS, a predicted membrane protein with 5 N-terminal transmembrane …

A defense system for defeating DDoS attacks in SDN based networks

…, A Chowdhary, S Pisharody, D Lu… - Proceedings of the 15th …, 2017 - dl.acm.org
Software-Defined Networking (SDN) is a network architecture that aims at providing high
flexibility through the decoupling of the network logic from the forwarding functions. The ease of …

Structures of the RNA polymerase-σ54 reveal new and conserved regulatory strategies

Y Yang, VC Darbari, N Zhang, D Lu, R Glyde, YP Wang… - Science, 2015 - science.org
Transcription by RNA polymerase (RNAP) in bacteria requires specific promoter recognition
by σ factors. The major variant σ factor (σ 54 ) initially forms a transcriptionally silent complex …