Management of severe perioperative bleeding: guidelines from the European Society of Anaesthesiology

…, CAA Santullano, E De Robertis… - European Journal of …, 2013 - journals.lww.com
The aims of severe perioperative bleeding management are three-fold. First, preoperative
identification by anamesis and laboratory testing of those patients for whom the perioperative …

A common plan for dorsoventral patterning in Bilateria

EM De Robertis, Y Sasai - Nature, 1996 - nature.com
Functional studies seem now to confirm, as first suggested by E. Geoffrey Saint-Hilaire in 1822,
that there was an inversion of the dorsoventral axis during animal evolution. A conserved …

DORSAL-VENTRAL PATTERNING AND NEURAL INDUCTION IN XENOPUS EMBRYOS

EM De Robertis, H Kuroda - Annu. Rev. Cell Dev. Biol., 2004 - annualreviews.org
… (which has not yet been identified molecularly) (De Robertis & Sasai 1996, Lall & Patel 2001).
… Coffinier & EM De Robertis, unpublished observations). Whereas Chordin expression is …

Connective-tissue growth factor (CTGF) modulates cell signalling by BMP and TGF-β

…, NI Ketpura, B Reversade, EM De Robertis - Nature cell …, 2002 - nature.com
e, RT-PCR analysis of whole embryo (WE), animal caps uninjected (AC control) or
injected with 50 pg of CTGF mRNA per blastomere at the 4-cell stage (AC CTGF). Animal cap …

[HTML][HTML] Dorsoventral patterning in Xenopus: inhibition of ventral signals by direct binding of chordin to BMP-4

S Piccolo, Y Sasai, B Lu, EM De Robertis - Cell, 1996 - cell.com
Chordin (Chd) is an abundant protein secreted by Spemann organizer tissue during
gastrulation. Chd antagonizes signaling by mature bone morphogenetic proteins (BMPs) by …

Xenopus chordin: a novel dorsalizing factor activated by organizer-specific homeobox genes

…, H Steinbeisser, D Geissert, LK Gont, EM De Robertis - Cell, 1994 - cell.com
… (E) is viewed from the dorsal side with anterior at top. (F)-(H) are lateral views. … This rescue
is dose dependent and sensitive to e-fold differences in the amount of injected mRNA. At low …

Molecular nature of Spemann's organizer: the role of the Xenopus homeobox gene goosecoid

…, B Blumberg, H Steinbeisser, EM De Robertis - Cell, 1991 - cell.com
This study analyzer, the function of the homeobox gene goosecold in Xenopus development.
First, we find that gooaecoid mFiNA distribution closely mimics the expected localization of …

[HTML][HTML] Frzb-1 is a secreted antagonist of Wnt signaling expressed in the Spemann organizer

…, T Bouwmeester, SH Kim, S Piccolo, EM De Robertis - Cell, 1997 - cell.com
Frzb-1 is a secreted protein containing a domain similar to the putative Wnt-binding region
of the frizzled family of transmembrane receptors. Frzb-1 is widely expressed in adult …

Management of severe perioperative bleeding: guidelines from the European Society of Anaesthesiology: first update 2016

…, C Aldecoa, G Barauskas, E De Robertis… - European Journal of …, 2017 - journals.lww.com
The management of perioperative bleeding involves multiple assessments and strategies to
ensure appropriate patient care. Initially, it is important to identify those patients with an …

Regulation of neural induction by the Chd and Bmp-4 antagonistic patterning signals in Xenopus

Y Sasai, B Lu, H Steinbeisser, EM De Robertis - Nature, 1995 - nature.com
IN Drosophila the amount of neurogenic ectoderm, from which the central nervous system (CNS)
derives, is regulated by a dorsal-ventral system of positional information in which two …