Stimulation of dopamine (DA) receptors in the striatum is essential for voluntary motor activity
and for the generation of plasticity at corticostriatal synapses. In the present study, mice …

Background and Purpose— The possible neuroprotective effect of endogenous γ-aminobutyric
acid (GABA) on the irreversible electrophysiological changes induced by in vitro …

Although metabotropic glutamate receptors (mGluRs) have been proposed to play a role in
corticostriatal long-term depression (LTD), the specific receptor subtype required for this form …

In the present study we have characterized a rat model of manganese (Mn) intoxication
leading to behavioral disinhibition in the absence of major motor alterations. These behavioral …

Background and Purpose—The aim of this study was to determinate the possible role of the
ionotropic glutamate receptor in the expression of irreversible electrophysiological changes …

In the present in vitro study of rat brain, we report that transient oxygen and glucose deprivation
(in vitro ischaemia) induced a post‐ischaemic long‐term synaptic potentiation (i‐LTP) at …

Several experimental data indicate that tissue plasminogen activator (tPA) is involved in
memory formation and synaptic plasticity in different brain areas. In the attempt to highlight the …

To investigate the role of phosphatidylinositol 3 kinase (PI3 kinase) in hippocampal synaptic
plasticity, we used whole-cell patch clamp recordings from rat CA1 neurons to determine …

An impaired complex II (succinate dehydrogenase, SD) striatal mitochondrial activity is one
of the prominent metabolic alterations in Huntington's disease (HD), and intoxication with 3-…

Several reports have shown that energy deprivation, as a result of hypoxia, hypoglycaemia
or ischaemia, depresses excitatory synaptic transmission in virtually all brain areas. How this …