Rationale Cortical γ-aminobutyric acid (GABA)ergic neurons contribute to the orchestration
of pyramidal neuron population firing as follows: (1) by releasing GABA on GABA A and …

Protracted social isolation in laboratory animals causes stress, which induces a variety of
behavioral abnormalities including increased aggressiveness, anxiety-related behaviors, …

A recent report suggests that the down-regulation of reelin and glutamic acid decarboxylase
(GAD 67 ) mRNAs represents 2 of the more consistent findings thus far described in post-…

Fifty-one tannins and forty-one flavonoids isolated from Oriental medicinal herbs were
evaluated for their antioxidant ability with a 1,1-diphenyl-2-picrylhydrazyl (DPPH) radical-…

Allopregnanolone (ALLO), is a brain endogenous neurosteroid that binds with high affinity
to γ-aminobutyric acid type A (GABA A ) receptors and positively modulates the action of …

BACKGROUND: Reelin and GAD 67 expression is downregulated in cortical interneurons
of schizophrenia (SZ) patients. This downregulation is probably mediated by epigenetic …

Social isolation (SI) of male mice lasting >4 weeks is associated with aggression toward
intruders and a down-regulation of brain allopregnanolone (Allo) content. SI of female mice fails …

The effects of tea (Camellia sinensis L.) of three types on excessive free radicals were
examined utilizing spin trapping, 1,1-diphenyl-2-picrylhydrazyl radical, lipid peroxidation, and …

Background Prenatal stress (PRS) is considered a risk factor for several neurodevelopmental
disorders including schizophrenia (SZ). An animal model involving restraint stress of …

Increasing evidence suggests that epigenetic dysfunction may account for the alteration of
gene transcription present in neuropsychiatric disorders such as schizophrenia (SZ), bipolar …