User profiles for Eyal Bengal

Eyal Bengal

Technion
Verified email at technion.ac.il
Cited by 4614

The p38 MAPK signaling pathway: a major regulator of skeletal muscle development

A Keren, Y Tamir, E Bengal - Molecular and cellular endocrinology, 2006 - Elsevier
Skeletal muscle development is regulated by extracellular growth factors that transmit largely
unknown signals into the cell affecting the muscle-transcription program. One intracellular …

A MyoD-generated feed-forward circuit temporally patterns gene expression during skeletal muscle differentiation

…, DA Bergstrom, FJ Dilworth, E Bengal… - Genes & …, 2004 - genesdev.cshlp.org
The development and differentiation of distinct cell types is achieved through the sequential
expression of subsets of genes; yet, the molecular mechanisms that temporally pattern gene …

[HTML][HTML] p38 MAPK in glucose metabolism of skeletal muscle: Beneficial or harmful?

E Bengal, S Aviram, T Hayek - International journal of molecular sciences, 2020 - mdpi.com
Skeletal muscles respond to environmental and physiological changes by varying their size,
fiber type, and metabolic properties. P38 mitogen-activated protein kinase (MAPK) is one of …

[HTML][HTML] p38 mitogen-activated protein kinase pathway promotes skeletal muscle differentiation: participation of the Mef2c transcription factor

A Zetser, E Gredinger, E Bengal - Journal of biological chemistry, 1999 - ASBMB
Differentiation of muscle cells is regulated by extracellular growth factors that transmit
largely unknown signals into the cells. Some of these growth factors induce mitogen-activated …

[HTML][HTML] A novel site for ubiquitination: the N‐terminal residue, and not internal lysines of MyoD, is essential for conjugation and degradation of the protein

K Breitschopf, E Bengal, T Ziv, A Admon… - The EMBO …, 1998 - embopress.org
The ubiquitin proteolytic pathway is a major system for selective protein degradation in
eukaryotic cells. One of the first steps in the degradation of a protein via this pathway involves …

[HTML][HTML] Mitogen-activated protein kinase pathway is involved in the differentiation of muscle cells

…, AN Gerber, Y Tamir, SJ Tapscott, E Bengal - Journal of Biological …, 1998 - ASBMB
The differentiation of muscle cells is controlled by the MyoD family of transcription factors.
This family is regulated by extracellular growth factors that transmit largely unknown signals …

Functional antagonism between c-Jun and MyoD proteins: a direct physical association

E Bengal, L Ransone, R Scharfmann, VJ Dwarki… - Cell, 1992 - cell.com
The product of the proto-oncogene Jun inhibits myogenesis. Constitutive expression of Jun
in myoblasts interferes with the expression and the function of MyoD protein. In transient …

Degradation of myogenic transcription factor MyoD by the ubiquitin pathway in vivo and in vitro: regulation by specific DNA binding

…, H Gonen, A Ciechanover, E Bengal - … and cellular biology, 1998 - Taylor & Francis
MyoD is a tissue-specific transcriptional activator that acts as a master switch for skeletal
muscle differentiation. Its activity is induced during the transition from proliferating, …

[HTML][HTML] CREB-binding protein/p300 activates MyoD by acetylation

…, I Naguibneva, C Weise, A Vervisch, E Bengal… - Journal of Biological …, 2000 - ASBMB
The myogenic protein MyoD requires two nuclear histone acetyltransferases, CREB-binding
protein (CBP)/p300 and PCAF, to transactivate muscle promoters. MyoD is acetylated by …

Role of the mammalian transcription factors IIF, IIS, and IIX during elongation by RNA polymerase II

E Bengal, O Flores, A Krauskopf… - Molecular and cellular …, 1991 - Taylor & Francis
We have used a recently developed system that allows the isolation of complexes competent
for RNA polymerase II elongation (E. Bengal, A. Goldring, and Y. Aloni, J. Biol. Chem. 264:…