User profiles for Eyasu Makonnen

Eyasu Makonnen

Professor of Pharmacology, Addis Ababa University
Verified email at aau.edu.et
Cited by 6180

[HTML][HTML] Systematic review of Ethiopian medicinal plants used for their anti-inflammatory and wound healing activities

D Nigussie, E Makonnen, TB Tufa, M Brewster… - Journal of …, 2021 - Elsevier
Ethnopharmacological relevance Plant materials are used worldwide as complementary
and alternative therapeutics for the treatment of various illnesses. In Ethiopia, folk medicines …

In vitro and in vivo anthelmintic activity of crude extracts of Coriandrum sativum against Haemonchus contortus

…, G Tilahun, A Debella, A Feleke, E Makonnen - Journal of …, 2007 - Elsevier
In vitro anthelmintic activities of crude aqueous and hydro-alcoholic extracts of the seeds of
Coriandrum sativum (Apiaceae) were investigated on the egg and adult nematode parasite …

Essential oils as topical anti-infective agents: A systematic review and meta-analysis

…, AG Mtewa, A Abebe, A Hymete, E Makonnen… - … therapies in medicine, 2019 - Elsevier
Objective This study summarized evidence on the efficacy and safety of essential oils (EOs)
in the treatment of topical infections. Design and setting Systematic review of clinical trials …

[HTML][HTML] Antibacterial and antifungal activities of Ethiopian medicinal plants: a systematic review

…, BA Legesse, A Fekadu, E Makonnen - Frontiers in …, 2021 - frontiersin.org
Background: Podoconiosis and lymphatic filariasis are the most common causes of lower limb
lymphoedema in the tropics. Many sufferers experience frequent painful episodes of acute …

Genetic polymorphism of CYP1A2 in Ethiopians affecting induction and expression: characterization of novel haplotypes with single-nucleotide polymorphisms in …

E Aklillu, JA Carrillo, E Makonnen, K Hellman… - Molecular …, 2003 - ASPET
CYP1A2 polymorphism has been well studied in white persons and Asians but not in Africans.
We performed CYP1A2 genotype and phenotype analysis using caffeine in Ethiopians …

[HTML][HTML] Sodium stibogluconate (SSG) & paromomycin combination compared to SSG for visceral leishmaniasis in East Africa: a randomised controlled trial

…, H Tafes, Y Mekonnen, E Makonnen… - PLoS neglected …, 2012 - journals.plos.org
Background Alternative treatments for visceral leishmaniasis (VL) are required in East Africa.
Paromomycin sulphate (PM) has been shown to be efficacious for VL treatment in India. …

[HTML][HTML] Geographical variation in the response of visceral leishmaniasis to paromomycin in East Africa: a multicentre, open-label, randomized trial

…, T Weldegebreal, S Tesfaye, E Makonnen… - PLoS neglected …, 2010 - journals.plos.org
Background Visceral leishmaniasis (VL) is a major health problem in developing countries.
The untreated disease is fatal, available treatment is expensive and often toxic, and drug …

Haemonchus contortus: in vitro and in vivo anthelmintic activity of aqueous and hydro-alcoholic extracts of Hedera helix

…, G Tilahun, A Debella, A Feleke, E Makonnen - Experimental …, 2007 - Elsevier
In vitro anthelmintic activity of crude extracts of the ripe fruits of Hedera helix was investigated
on eggs and adult nematode parasites Haemonchus contortus. Aqueous extract of H. helix …

[HTML][HTML] Importance of ethnicity, CYP2B6 and ABCB1 genotype for efavirenz pharmacokinetics and treatment outcomes: a parallel-group prospective cohort study in …

E Ngaimisi, A Habtewold, O Minzi, E Makonnen… - PloS one, 2013 - journals.plos.org
Objectives We evaluated the importance of ethnicity and pharmacogenetic variations in
determining efavirenz pharmacokinetics, auto-induction and immunological outcomes in two …

[HTML][HTML] Effect of Achyranthes aspera L. on fetal abortion, uterine and pituitary weights, serum lipids and hormones

W Shibeshi, E Makonnen, L Zerihun, A Debella - African health sciences, 2006 - ajol.info
Back ground: The practice of traditional medicine for the control of fertility in rural Ethiopia is
based on folk use of numerous antifertility herbs and Achyranthes aspera is one of these …