User profiles for F. J. Barrantes

Francisco J. Barrantes

head, Laboratory of Molecular Neurobiology, Biomedical Res. Institute, UCA-CONICET …
Verified email at uca.edu.ar
Cited by 9964

[HTML][HTML] How cholesterol interacts with membrane proteins: an exploration of cholesterol-binding sites including CRAC, CARC, and tilted domains

J Fantini, FJ Barrantes - Frontiers in physiology, 2013 - frontiersin.org
The plasma membrane of eukaryotic cells contains several types of lipids displaying high
biochemical variability in both their apolar moiety (eg, the acyl chain of glycerolipids) and their …

[HTML][HTML] Sphingolipid/cholesterol regulation of neurotransmitter receptor conformation and function

J Fantini, FJ Barrantes - Biochimica et Biophysica Acta (BBA) …, 2009 - Elsevier
Like all other monomeric or multimeric transmembrane proteins, receptors for neurotransmitters
are surrounded by a shell of lipids which form an interfacial boundary between the …

[HTML][HTML] Disclosure of cholesterol recognition motifs in transmembrane domains of the human nicotinic acetylcholine receptor

CJ Baier, J Fantini, FJ Barrantes - Scientific reports, 2011 - nature.com
Cholesterol influences ion-channel function, distribution and clustering in the membrane,
endocytosis and exocytic sorting of the nicotinic acetylcholine receptor (AChR). We report the …

Effects of lipids on acetylcholine receptor. Essential need of cholesterol for maintenance of agonist-induced state transitions in lipid vesicles

M Criado, H Eibl, FJ Barrantes - Biochemistry, 1982 - ACS Publications
M. Criado, H. Eibl, and FJ Barrantes* abstract: The effects of lipids on the maintenance of
characteristic functional properties of the acetylcholine receptor during the course of …

Immobilized lipid in acetylcholine receptor-rich membranes from Torpedo marmorata.

D Marsh, FJ Barrantes - Proceedings of the National …, 1978 - National Acad Sciences
The lipid environment of acetylcholine receptor-rich membranes from Torpedo marmorata
has been studied with spin labels. The electron spin resonance spectra of both stearic acid …

[HTML][HTML] Deficits in cholinergic neurotransmission and their clinical correlates in Parkinson's disease

S Perez-Lloret, FJ Barrantes - NPJ Parkinson's disease, 2016 - nature.com
In view of its ability to explain the most frequent motor symptoms of Parkinson’s Disease (PD),
degeneration of dopaminergic neurons has been considered one of the disease’s main …

Structural basis for lipid modulation of nicotinic acetylcholine receptor function

FJ Barrantes - Brain Research Reviews, 2004 - Elsevier
The nicotinic acetylcholine receptor (AChR) is the archetype molecule in the superfamily of
ligand-gated ion channels (LGIC). Members of this superfamily mediate fast intercellular …

Functional properties of the acetylcholine receptor incorporated in model lipid membranes. Differential effects of chain length and head group of phospholipids on …

M Criado, H Eibl, FJ Barrantes - Journal of Biological Chemistry, 1984 - ASBMB
Torpedo acetylcholine receptor was reconstituted into liposomes of pure synthetic lipids in
order to study the influence of the lipid environment on affinity state transitions and the ion …

Nanoscale organization of nicotinic acetylcholine receptors revealed by stimulated emission depletion microscopy

RR Kellner, CJ Baier, KI Willig, SW Hell, FJ Barrantes - Neuroscience, 2007 - Elsevier
Acetylcholine receptor (AChR) supramolecular aggregates that have hitherto only been
accessible to examination by electron microscopy were imaged with stimulated emission …

[HTML][HTML] A mirror code for protein-cholesterol interactions in the two leaflets of biological membranes

…, C Di Scala, LS Evans, PTF Williamson, FJ Barrantes - Scientific reports, 2016 - nature.com
… This would suggest that cholesterol-mediated oligomerization is mediated by cholesterol/cholesterol
interactions, such as those proposed by Fantini and Barrantes 9 , rather than …