The cannabinoid CB1 receptor antagonist SR141716 increases Acrp30 mRNA expression in adipose tissue of obese fa/fa rats and in cultured adipocyte cells
…, JP Maffrand, G Le Fur, F Oury-Donat… - Molecular …, 2003 - ASPET
This study investigates the effects of SR141716, a selective CB 1 receptor antagonist that
reduces food intake and body weight of rodents, on Acrp30 mRNA expression in adipose tissue…
reduces food intake and body weight of rodents, on Acrp30 mRNA expression in adipose tissue…
Rimonabant reduces obesity-associated hepatic steatosis and features of metabolic syndrome in obese Zucker fa/fa rats
…, F Oury-Donat, JP Maffrand, B Scatton, F Lacheretz… - Hepatology, 2007 - journals.lww.com
This study investigated the effects of rimonabant (SR141716), an antagonist of the cannabinoid
receptor type 1 (CB1), on obesity-associated hepatic steatosis and related features of …
receptor type 1 (CB1), on obesity-associated hepatic steatosis and related features of …
[HTML][HTML] SSR180711, a novel selective α7 nicotinic receptor partial agonist:(II) efficacy in experimental models predictive of activity against cognitive symptoms of …
…, R Steinberg, J Stemmelin, F Oury-Donat… - …, 2007 - nature.com
… During this recall session, the objects A and B were placed in the open field, and the time
that animal took to explore the familiar object A (F) and the novel object B (N) were recorded. A …
that animal took to explore the familiar object A (F) and the novel object B (N) were recorded. A …
Biochemical and pharmacological activities of SR 142948A, a new potent neurotensin receptor antagonist
D Gully, B Labeeuw, R Boigegrain, F Oury-Donat… - … of Pharmacology and …, 1997 - ASPET
… The HT 29 cell line (obtained from the American Type Culture Collection, Rockville, MD)
was cultured under similar conditions in Dulbecco’s modified Eagle’s medium/F-12 medium …
was cultured under similar conditions in Dulbecco’s modified Eagle’s medium/F-12 medium …
[HTML][HTML] Neurochemical, electrophysiological and pharmacological profiles of the selective inhibitor of the glycine transporter-1 SSR504734, a potential new type of …
…, R Alonso, P Avenet, F Oury-Donat… - …, 2005 - nature.com
… Administration of SSR504734 (10 mg/kg ip) produced a rapid and sustained increase in
PFC extracellular levels of glycine (F(1,16)=10.23, P<0.01 and F(12,192)=8.03, P<0.001 for the …
PFC extracellular levels of glycine (F(1,16)=10.23, P<0.01 and F(12,192)=8.03, P<0.001 for the …
[HTML][HTML] SSR180711, a novel selective α7 nicotinic receptor partial agonist:(1) binding and functional profile
…, R Steinberg, G Griebel, F Oury-Donat… - …, 2007 - nature.com
In this paper, we report on the pharmacological and functional profile of SSR180711 (1, 4-Diazabicyclo
[3.2. 2] nonane-4-carboxylic acid, 4-bromophenyl ester), a new selective α7 …
[3.2. 2] nonane-4-carboxylic acid, 4-bromophenyl ester), a new selective α7 …
The cannabinoid CB1 receptor antagonist rimonabant (SR141716) inhibits cell proliferation and increases markers of adipocyte maturation in cultured mouse 3T3 …
…, G Elachouri, B Scatton, G Le Fur, F Oury-Donat… - Molecular …, 2006 - ASPET
Adipocyte cell proliferation is an important process in body fat mass development in obesity.
Adiponectin or Acrp30 is an adipocytokine exclusively expressed and secreted by adipose …
Adiponectin or Acrp30 is an adipocytokine exclusively expressed and secreted by adipose …
Neurotensin is an antagonist of the human neurotensin NT2 receptor expressed in Chinese hamster ovary cells
N Vita, F Oury-Donat, P Chalon, M Guillemot… - European journal of …, 1998 - Elsevier
The human levocabastine-sensitive neurotensin NT 2 receptor was cloned from a cortex
cDNA library and stably expressed in Chinese hamster ovary (CHO) cells in order to study its …
cDNA library and stably expressed in Chinese hamster ovary (CHO) cells in order to study its …
Characterization of SSR103800, a selective inhibitor of the glycine transporter-1 in models predictive of therapeutic activity in schizophrenia
…, B Biton, R Steinberg, M Sevrin, F Oury-Donat… - Pharmacology …, 2008 - Elsevier
On native human, rat and mouse glycine transporter-1(GlyT1), SSR130800 behaves as a
selective inhibitor with IC50 values of 1.9, 5.3 and 6.8 nM, respectively. It reversibly blocked …
selective inhibitor with IC50 values of 1.9, 5.3 and 6.8 nM, respectively. It reversibly blocked …
Effects of the β3-adrenoceptor (Adrb3) agonist SR58611A (amibegron) on serotonergic and noradrenergic transmission in the rodent: relevance to its antidepressant …
…, M Didier, P Avenet, G Le Fur, F Oury-Donat… - Neuroscience, 2008 - Elsevier
SR58611A is a selective β 3 -adrenoceptor (Adrb3) agonist which has demonstrated
antidepressant and anxiolytic properties in rodents. The present study confirmed the detection of …
antidepressant and anxiolytic properties in rodents. The present study confirmed the detection of …