Rimonabant reduces obesity-associated hepatic steatosis and features of metabolic syndrome in obese Zucker fa/fa rats
…, M Arnone, T Croci, P Soubrié, F Oury-Donat… - Hepatology, 2007 - journals.lww.com
This study investigated the effects of rimonabant (SR141716), an antagonist of the cannabinoid
receptor type 1 (CB1), on obesity-associated hepatic steatosis and related features of …
receptor type 1 (CB1), on obesity-associated hepatic steatosis and related features of …
[HTML][HTML] SSR180711, a novel selective α7 nicotinic receptor partial agonist:(II) efficacy in experimental models predictive of activity against cognitive symptoms of …
…, R Steinberg, J Stemmelin, F Oury-Donat… - …, 2007 - nature.com
SSR180711 (4-bromophenyl 1, 4diazabicyclo (3.2. 2) nonane-4-carboxylate, monohydrochloride)
is a selective α7 nicotinic receptor (n-AChR) partial agonist. Based on the purported …
is a selective α7 nicotinic receptor (n-AChR) partial agonist. Based on the purported …
Biochemical and pharmacological activities of SR 142948A, a new potent neurotensin receptor antagonist
D Gully, B Labeeuw, R Boigegrain, F Oury-Donat… - … of Pharmacology and …, 1997 - ASPET
SR 142948A, 2-{[5-(2,6-dimethoxyphenyl)-1-(4-(N-(3-dimethylaminopropyl)-N-methylcarbamoyl)-2-isopropylphenyl)-1H-pyrazole-3-carbonyl]amino}adamantane-2-carboxylic
acid, …
acid, …
[HTML][HTML] Neurochemical, electrophysiological and pharmacological profiles of the selective inhibitor of the glycine transporter-1 SSR504734, a potential new type of …
…, R Alonso, P Avenet, F Oury-Donat… - …, 2005 - nature.com
Noncompetitive N-methyl-D-aspartate (NMDA) blockers induce schizophrenic-like symptoms
in humans, presumably by impairing glutamatergic transmission. Therefore, a compound …
in humans, presumably by impairing glutamatergic transmission. Therefore, a compound …
Biochemical and pharmacological activities of SSR 146977, a new potent nonpeptide tachykinin NK3 receptor antagonist
…, C Gueudet, JC Michaud, F Oury-Donat… - Canadian journal of …, 2002 - cdnsciencepub.com
Le SSR 146977 est un puissant et sélectif antagoniste des récepteurs NK 3 aux tachykinines.
Dans les cellules ovariennes de hamster chinois exprimant le récepteur NK 3 humain, le …
Dans les cellules ovariennes de hamster chinois exprimant le récepteur NK 3 humain, le …
[HTML][HTML] SSR180711, a novel selective α7 nicotinic receptor partial agonist:(1) binding and functional profile
…, R Steinberg, G Griebel, F Oury-Donat… - …, 2007 - nature.com
In this paper, we report on the pharmacological and functional profile of SSR180711 (1, 4-Diazabicyclo
[3.2. 2] nonane-4-carboxylic acid, 4-bromophenyl ester), a new selective α7 …
[3.2. 2] nonane-4-carboxylic acid, 4-bromophenyl ester), a new selective α7 …
The cannabinoid CB1 receptor antagonist rimonabant (SR141716) inhibits cell proliferation and increases markers of adipocyte maturation in cultured mouse 3T3 …
…, G Elachouri, B Scatton, G Le Fur, F Oury-Donat… - Molecular …, 2006 - ASPET
Adipocyte cell proliferation is an important process in body fat mass development in obesity.
Adiponectin or Acrp30 is an adipocytokine exclusively expressed and secreted by adipose …
Adiponectin or Acrp30 is an adipocytokine exclusively expressed and secreted by adipose …
Neurotensin is an antagonist of the human neurotensin NT2 receptor expressed in Chinese hamster ovary cells
N Vita, F Oury-Donat, P Chalon, M Guillemot… - European journal of …, 1998 - Elsevier
The human levocabastine-sensitive neurotensin NT 2 receptor was cloned from a cortex
cDNA library and stably expressed in Chinese hamster ovary (CHO) cells in order to study its …
cDNA library and stably expressed in Chinese hamster ovary (CHO) cells in order to study its …
Characterization of SSR103800, a selective inhibitor of the glycine transporter-1 in models predictive of therapeutic activity in schizophrenia
…, B Biton, R Steinberg, M Sevrin, F Oury-Donat… - Pharmacology …, 2008 - Elsevier
On native human, rat and mouse glycine transporter-1(GlyT1), SSR130800 behaves as a
selective inhibitor with IC50 values of 1.9, 5.3 and 6.8 nM, respectively. It reversibly blocked …
selective inhibitor with IC50 values of 1.9, 5.3 and 6.8 nM, respectively. It reversibly blocked …
Selective blockade of neurokinin-2 receptors produces antidepressant-like effects associated with reduced corticotropin-releasing factor function
The present study investigated the effects of the selective neurokinin-2 (NK 2 ) receptor
antagonist SR48968 in behavioral, electrophysiological, and biochemical tests sensitive to the …
antagonist SR48968 in behavioral, electrophysiological, and biochemical tests sensitive to the …