An accurate blood‐based RAS mutation assay to determine eligibility of metastatic colorectal
cancer ( mCRC ) patients for anti‐ EGFR therapy would benefit clinical practice by better …

The arousing and motor-activating effects of psychostimulants are mediated by multiple
systems. In Drosophila, dopaminergic transmission is involved in mediating the arousing effects …

Background Rett Syndrome (RTT) is an Autism Spectrum Disorder and the leading cause of
mental retardation in females. RTT is caused by mutations in the Methyl CpG-Binding Protein…

Homeobox genes are regulators of place-dependent morphogenesis and play important
roles in controlling the expression patterns of cell adhesion molecules (CAMs). To identify …

In an effort to determine whether homeobox genes modulate the activity of the promoter of
the mouse neural cell adhesion molecule (N-CAM) gene, we have carried out a series of …

CfDNA samples from colon (mCRC) and non-small cell lung cancers (NSCLC)(CIRCAN
cohort) were compared using three platforms: droplet digital PCR (ddPCR, Biorad); BEAMing/…

Pax-3 is a member of the Pax family of transcription factors involved in transcriptional control
events during embryonic development. Here we report a functional dissection of the Pax-3 …

Circulating tumor DNA (ctDNA) has emerged as a non-invasive “liquid biopsy” for early breast
cancer diagnosis. We evaluated the suitability of ctDNA analysis in the diagnosis of early …

Among the many factors involved in regulation of chondrogenesis, bone morphogenetic
proteins (BMPs) and members of the Sox and homeobox transcription factor families have been …

The cell adhesion molecule L1 mediates neurite outgrowth and fasciculation during
embryogenesis and mutations in its gene have been linked to a number of human congenital …