The interplay between the glucocorticoid receptor and nuclear factor-κB or activator protein-1: molecular mechanisms for gene repression

…, W Vanden Berghe, G Haegeman - Endocrine …, 2003 - academic.oup.com
The inflammatory response is a highly regulated physiological process that is critically important
for homeostasis. A precise physiological control of inflammation allows a timely reaction …

Interleukin-6, a mental cytokine

…, R Clinckers, J De Keyser, G Haegeman… - Brain research …, 2011 - Elsevier
Almost a quarter of a century ago, interleukin-6 (IL-6) was discovered as an inflammatory
cytokine involved in B cell differentiation. Today, IL-6 is recognized to be a highly versatile …

Regulation of the transcriptional activity of the nuclear factor-κB p65 subunit

…, S Notebaert, WV Berghe, G Haegeman - Biochemical …, 2002 - Elsevier
Nuclear factor-κB (NF-κB) is well known for its role in inflammation, immune response, control
of cell division and apoptosis. The function of NF-κB is primarily regulated by IκB family …

Complete nucleotide sequence of SV40 DNA

W Fiers, R Contreras, G Haegeman, R Rogiers… - Nature, 1978 - nature.com
… The end is the junction between the Hind fragments B and G. The different Hind fragments
are indicated. The initiation codon for t and T antigens is boxed, as are the respective termin…

Complete nucleotide sequence of bacteriophage MS2 RNA: primary and secondary structure of the replicase gene

W Fiers, R Contreras, F Duerinck, G Haegeman… - Nature, 1976 - nature.com
… It starts with the initiation codon A–U–G and ends with the termination codon U–A–G; these
regions have been published before*****". Figure 2 also shows sites which are sensitive to …

[HTML][HTML] Peroxisome proliferator-activated receptor α negatively regulates the vascular inflammatory gene response by negative cross-talk with transcription factors NF …

…, JC Fruchart, A Tedgui, G Haegeman… - Journal of Biological …, 1999 - ASBMB
Interleukin-6 (IL-6) is a pleiotropic cytokine, whose plasma levels are elevated in
inflammatory diseases such as atherosclerosis. We have previously reported that peroxisome …

[HTML][HTML] Transcriptional activation of the NF‐κB p65 subunit by mitogen‐and stress‐activated protein kinase‐1 (MSK1)

…, P Van Damme, WV Berghe, G Haegeman - The EMBO …, 2003 - embopress.org
Nuclear factor κB (NF‐κB) is one of the key regulators of transcription of a variety of genes
involved in immune and inflammatory responses. NF‐κB activity has long been thought to be …

Nucleotide sequence of the gene coding for the bacteriophage MS2 coat protein

WM Jou, G Haegeman, M Ysebaert, W Fiers - Nature, 1972 - nature.com
By characterization of fragments, isolated from a nuclease digest of MS2 RNA, the entire
nucleotide sequence of the coat gene was established. A “flower”-like model is proposed for the …

[HTML][HTML] p38 and extracellular signal-regulated kinase mitogen-activated protein kinase pathways are required for nuclear factor-κB p65 transactivation mediated by …

…, ML Schmitz, W Fiers, G Haegeman - Journal of Biological …, 1998 - ASBMB
Interleukin-6 (IL-6) is a pleiotropic cytokine, which is involved in inflammatory and immune
responses, acute phase reactions, and hematopoiesis. In the mouse fibrosarcoma cell line …

The p38/RK mitogen‐activated protein kinase pathway regulates interleukin‐6 synthesis response to tumor necrosis factor.

…, S Plaisance, JC Lee, G Haegeman… - The EMBO …, 1996 - embopress.org
… Lysates were cleared by centrifugation at 10 000 g for 10 min and subjected to
immunoprecipitation with the appropriate antisera for 2 h. Precipitates were collected by adsorption …