Objectives: The first tissue engineered decellularized porcine heart valve, Synergraft® (Cryolife
Inc., USA) was introduced in Europe as an alternative to conventional biological valves. …

OBJECTIVE: We compared 3 different decellularization protocols in porcine heart valves for
efficiency of complete cell removal and potential for recellularization. METHODS: Porcine …

… It is Weigel's gift to be able to interleaf the spiritual and secular aspects of Wojtyla's education
… "Weigel's book is not only a major piece of scholarship, but a cracking good story. Rarely …

Background Tissue engineering of heart valves should avoid the disadvantages of
conventional prostheses. In this study we tested different decellularization procedures for their …

Background— Rheumatoid arthritis (RA) is characterized by increased cardiovascular
morbidity and mortality that cannot be explained solely by traditional cardiovascular risk factors. …

… Ditzenberger, my executive assistant (and first baseman) at the Ethics and Public Policy
Center, prepared the manuscript for publication (with some indexing help from Gwyneth Weigel) …

Heme oxygenase-1 (HO-1) is an inducible enzyme that degrades heme to carbon monoxide,
iron ions, and biliverdin. Its expression can be induced by 15-deoxy-Δ 12,14 prostaglandin-…

Background L‐Arginine‐depleted environments accompanying ischaemia–reperfusion
enhance superoxide production, leading to the formation of reactive oxygen species and a …

Results: In contrast to the Synergraft, complete cell removal and elimination of the a-gal epitope
was achieved with the new decellularization method. Numerous adherent and activated …

The activity of heme oxygenase enzymes (HOs) is responsible for the endogenous source
of carbon monoxide (CO). Their activities can be inhibited by tin protoporphyrin-IX (SnPPIX). …