In this report, we investigate the role of the RNA-binding protein HuR during skeletal
myogenesis. At the onset of myogenesis in differentiating C2C12 myocytes and in vivo in …

Granulosa cell tumors of the ovary (GCT) represent ~5% of malignant ovarian tumors. The
adult form is defined by a mutation in the FOXL2 gene. GCT exhibit many of the features of …

It has been proposed that dimerization of identical receptor subunits by growth hormone (GH)
is the mechanism of signal transduction across the cell membrane. We present here data …

Previously, we reported the presence of dual promoters, referred to as distal (DP) and
proximal, with a negative regulatory element between them in the mouse μ-opioid receptor (mor) …

Granulosa cell tumors (GCT) of the ovary are rare, hormonally-active neoplasms characterized
by endocrine manifestations, an indolent course and late relapse. Chemotherapy and …

The primary function of the adenovirus ElA-region genes is to activate other adenoviral genes
during a permissive viral infection by modifying the host cell transcriptional apparatus 1,2 . …

Skeletal myoblasts have their origin early in embryogenesis within specific somites.
Determined myoblasts are committed to a myogenic fate; however, they only differentiate and …

… In an effort to further understand the transcriptional properties of Rev-erbAtu LBD or E region,
we used the properties of the GALVPIG chimera, a potent transcriptional activator, to study …

The skeletal and cardiac alpha-actin genes are coexpressed in muscle development but
exhibit distinctive tissue-specific patterns of expression. We used an in vivo competition assay …

Transfection into myogenic and nonmyogenic cell lines was used to investigate the transcriptional
regulation of the human α-skeletal actin gene. We demonstrated that 1,300 base pairs …