The cDNAs encoding the human bone morphogenetic proteins BMP-2 and BMP-4 in an
eukaryotic expression vector were permanently transferred into the murine mesenchymal …

Abnormal accumulation of soluble oligomers of amyloid β (Aβ) is believed to cause
malfunctioning of neurons in Alzheimer's disease. It has been shown that Aβ oligomers impair …

Two different phosphonic acid monolayer films for immobilization of bioactive molecules
such as the protein BMP-2 on titanium surfaces have been prepared. Monolayers of (11-…

Tissue regeneration requires the recruitment of adult stem cells and their differentiation into
mature committed cells. In this study we describe what we believe to be a novel approach for …

The complete amino acid sequence of the selenoprotein phospholipid-hydroperoxide
glutathione peroxidase (PHGPX) from pig heart has been deduced from the corresponding …

Imatinib mesylate (GLEEVEC, GLIVEC, formerly STI571) has demonstrated unprecedented
efficacy as first-line therapy for treatment for all phases of chronic myelogenous leukemia …

Tendons and ligaments are elastic collagenous tissues with similar composition and hierarchical
structure, contributing to motion. Their strength is related to the number and size of the …

Escherichacoli was genetically engineered to produce recombinant human bone
morphogenetic protein-2 (rhBMP-2) in a non-active aggregated form using a temperature-inducible …

Dopamine D2 receptor blockade has been an obligate mechanism of action present in all
medications that effectively treat positive symptoms of schizophrenia (eg, delusions and …

This review focuses on the molecular aspects of osteogenesis and chondrogenesis as they
relate to cellular and developmental levels. We discuss BMP (bone morphogenetic protein)-…