Although fatigue is the most common symptom reported by cancer patients and has serious
adverse effects on quality of life, it remains poorly understood. A survey was designed to …

METHOTREXATE, the most widely used antimetabolite in cancer chemotherapy, has an
essential role in the treatment of such diverse diseases as acute lymphocytic leukemia, non-…

A second reason for the intense concern with mechanisms of drug action stems from the
insights such work provide re-garding normal biological processes. For example, the first …

Purpose. This survey was designed to confirm the prevalence and duration of fatigue in the
cancer population and to assess its physical, mental, social, and economic impacts on the …

Purpose: To evaluate the proposed cancer-related fatigue (CRF) diagnostic criteria in a sample
of cancer survivors. More accurate prevalence estimates of CRF may result in improved …

Fatigue is a complex, multifactorial disorder with physical, mental, and psychological dimensions
that has been associated with diminished quality of life (QOL) in patients with cancer. …

Fatigue is the most commonly reported symptom in cancer patients and has a profound
effect on patient quality of life (QOL). The Fatigue-1 and Fatigue-2 surveys performed by the …

… Andrew Sparber, RN, MS, CS, Larry Bauer, RN, MA, Gregory Curt, MD, David Eisenberg,
MD… Gregory Curt, MD, is the clinical director at the NIH ',v National Cancer Institute (NC/). David …

Genistein (5,7,4′-trihydroxyisoflavone), an isoflavinoid found in soy beans, has been identified
as potentially causal for the low incidence of metastatic prostate cancer (PCa) in certain …

Background. AZD1480 is a novel agent that inhibits Janus‐associated kinases 1 and 2 (JAK1
and JAK2). The primary objective of this phase I study was to investigate the safety and …