Cannabis sativa and related products are widely used, but their potential to cause significant
clinical interactions remains unclear, particularly for cannabinoid-enriched or otherwise …

Background Cannabis legalization has enabled increased consumption in older adults. Age-related
mental, physical, and physiological changes may lead to differences in effects of …

There are ten mammalian diacylglycerol kinases (DGKs) whose primary role is to terminate
diacylglycerol (DAG) signaling. However, it is becoming increasingly apparent that DGKs …

Syntrophins are scaffolding proteins that link signaling molecules to dystrophin and the
cytoskeleton. We previously reported that syntrophins interact with diacylglycerol kinase-ζ (DGK-ζ…

Activation of Rac1 GTPase signaling is stimulated by phosphorylation and release of RhoGDI
by the effector p21-activated kinase 1 (PAK1), but it is unclear what initiates this potential …

Syntrophins are scaffold proteins that regulate the subcellular localization of diacylglycerol
kinase ζ (DGK-ζ), an enzyme that phosphorylates the lipid second-messenger diacylglycerol …

Introduction Concurrent use of tobacco and cannabis may impede successful cigarette
smoking cessation. This study examined whether changes in cannabis use frequency were …

Arylamine N-acetyltransferases (NATs) catalyze the biotransformation of a variety of arylamine
drugs and carcinogens and may play diametrically opposing roles in enhancing either the …

Cannabis sativa contains more than 120 cannabinoids and 400 terpene compounds (ie,
phytomolecules) present in varying amounts. Cannabis is increasingly available for legal …

The fusion of mononuclear myoblasts into multinucleated myofibers is essential for the
formation and growth of skeletal muscle. Myoblast fusion follows a well‐defined sequence of …