MATERIALS AND METHODS Materials. Unlabeled FPP was from USF (Tampa, FL),[1-3H]
FPP was from DuPont New England Nuclear Research Products (Wilmington, DE), assay stop …

Neuropeptide Y (NPY) is one of the most abundant peptide transmitters in the mammalian
brain. In the periphery it is costored and coreleased with norepinephrine from sympathetic …

Atypical dopamine reuptake inhibitors, such as modafinil, are used for the treatment of
sleeping disorders and investigated as potential therapeutics against cocaine addiction and for …

The worldwide increase in cognitive decline, both in aging and with psychiatric disorders,
warrants a search for pharmacological treatment. Although dopaminergic treatment …

… Leban.l Thomas Spector,* and David J. T. Porter* … W., Plattner, JJ, Rittenhouse, J. W.,
Turón, M, Wideburg, N., Kohlbrenner, W. E., Simmer, R., Helfrich, R., Paul, D. …

Aging-related neurological deficits negatively impact mental health, productivity, and social
interactions leading to a pronounced socioeconomic burden. Since declining brain …

Modafinil is a wake promoting compound with high potential for cognitive enhancement. It is
targeting the dopamine transporter (DAT) with moderate selectivity, thereby leading to …

Pergamon SOO40-4039(96)00018-4 Design and Synthesis of Novel Protease Inhibitors.
Tripeptide cx’$‘-Epoxyketones as Nanomolar Page 1 Pergamon Tetrahedron Letters, Vol. 37 …

The high structural similarity, especially in transmembrane regions, of dopamine,
norepinephrine, and serotonin transporters, as well as the lack of all crystal structures of human …

Peptide analogs of neuropeptide Y (NPY) with a Tyr-32 and Leu-34 replacement resulted in
the decapeptide TyrIleAsnLeuIleTyrArgLeuArgTyr-NH2 (9; Table 1) and a 3700-fold …