Microglia are brain‐resident macrophages forming the first active immune barrier in the
central nervous system. They fulfill multiple functions across development and adulthood and …

ApoE is the major lipid and cholesterol carrier in the CNS. There are three major human
polymorphisms, apoE2, apoE3, and apoE4, and the genetic expression of APOE4 is one of the …

The pro-inflammatory immune response driven by microglia is a key contributor to the
pathogenesis of several neurodegenerative diseases. Though the research of microglia spans …

Activation of microglia and inflammation-mediated neurotoxicity are suggested to play a
decisive role in the pathogenesis of several neurodegenerative disorders. Activated microglia …

We have injected lipopolysaccharide (LPS) into the nigrostriatal pathway of rats in order to
address the role of inflammation in Parkinson's disease (PD). LPS induced a strong …

In this review, we have tried to summarize most available data dealing with the aquaporin (AQP)
family of water channels in the CNS. Two aquaporins have been identified so far in the …

Inflammatory response induced by microglia plays a critical role in the demise of neuronal
populations in neuroinflammatory diseases. Although the role of toll-like receptor 4 (TLR4) in …

Astrocytes and aquaporin-4 (AQP4) play a significant role in brain ion homeostasis.
Consequently the regulation of AQP4 mRNA in the CNS after different neurological insults was of …

Inflammation could be involved in some neurodegenerative disorders that accompany signs
of inflammation. However, because sensitivity to inflammation is not equal in all brain …

Molecular diversity of microglia, the resident immune cells in the CNS, is reported. Whether
microglial subsets characterized by the expression of specific proteins constitute subtypes …