… DNA topoisomerase II was inhibited gradually starting at 20 /j\i with complete inhibition at
high (80, ISO, and 370 /-/M) concentrations of genistein. It is interesting that genistein to tally …

Molecular mechanisms underlying sarcopenia, the age-related loss of skeletal muscle mass
and function, remain unclear. To identify molecular changes that correlated best with …

This essay examines the thought that our right actions have moral worth only if we perform
them for the right reasons. It argues against the view, often ascribed to Kant, that morally …

Estrogen-related receptor γ (ERRγ) regulates the perinatal switch to oxidative metabolism in
the myocardium. We wanted to understand the significance of induction of ERRγ expression …

… of Oxford University Press in the UK and in certain other countries © Julia Markovits 2014 …
Jay Wallace. I’ve had opportunities to present some of the work represented in the book to …

The antitrypanosomal and antifiliarial drug suramin is currently under investigation for treatment
of advanced malignancies including prostatic cancer, adrenocortical cancer, and some …

The effect of cyanomorpholinyldoxorubicin, morpholinyldoxorubicm, doxorubicin, and
Actinomycin D were studied on purified mouse leukemia(Li 21 0) DNA topoisomerases I and II. …

Persistent expression of certain oncogenes is required for tumor maintenance. This phenotype
is referred to as oncogene addiction and has been clinically validated by anticancer …

The search for novel therapeutic interventions for viral disease is a challenging pursuit,
hallmarked by the paucity of antiviral agents currently prescribed. Targeting of viral proteins has …

The DNA unwinding effects of some 9-aminoacridine derivatives were compared under
reaction conditions that could be used to study drug-induced topoisomerase II inhibition. An …