User profiles for J P Dilger

James P Dilger

Stony Brook University
Verified email at stonybrook.edu
Cited by 4078

Transport of protons across membranes by weak acids.

SG McLaughlin, JP Dilger - Physiological reviews, 1980 - journals.physiology.org
Many weak acids transport protons across both artificial lipid bilayers and biological
membranes. These hydrogen ion carriers-proton ionophores or “protonophores,” as they are …

Effects of local anesthetics on cancer cells

H Liu, JP Dilger, J Lin - Pharmacology & therapeutics, 2020 - Elsevier
Local anesthetics are widely used during clinical cancer surgeries. Studies have suggested
that the use and the type of anesthesia affect cancer outcomes. In vivo studies and clinical …

[HTML][HTML] Effect of Propofol on breast Cancer cell, the immune system, and patient outcome

R Li, H Liu, JP Dilger, J Lin - BMC anesthesiology, 2018 - Springer
Breast cancer is the second leading cause of cancer death in women. Surgery is the first
line of treatment for breast cancer. Retrospective clinical studies suggest that the type of …

Whole cell currents and mechanical responses of isolated outer hair cells

J Santos-Sacchi, JP Dilger - Hearing research, 1988 - Elsevier
Outer hair cells (OHCs) exhibit electrically induced cell movements which are considered to
enhance the frequency selectivity and sensitivity of basilar membrane vibration. Using …

The effects of bilayer thickness and tension on gramicidin single-channel lifetime

JR Elliott, D Needham, JP Dilger, DA Haydon - Biochimica et Biophysica …, 1983 - Elsevier
Measurements have been made of gramicidin single-channel lifetimes in monoacylglycerol
bilayers chosen so that their thickness ranged from above to below the length of the …

The dielectric constant of phospholipid bilayers and the permeability of membranes to ions

JP Dilger, SGA McLaughlin, TJ McIntosh, SA Simon - Science, 1979 - science.org
The Born charging equation predicts that the permeability of a phospholipid bilayer membrane
to ions should depend markedly on the dielectric constant of the membrane. Increasing …

[HTML][HTML] Effects of local anesthetics on breast cancer cell viability and migration

R Li, C Xiao, H Liu, Y Huang, JP Dilger, J Lin - BMC cancer, 2018 - Springer
Background Breast cancer accounts for nearly a quarter of all cancers in women worldwide,
and more than 90% of women diagnosed with breast cancer undergo mastectomy or breast-…

A pan-cancer-bioinformatic-based literature review of TRPM7 in cancers

H Liu, JP Dilger, J Lin - Pharmacology & Therapeutics, 2022 - Elsevier
TRPM7, a divalent cation-selective channel with kinase domains, has been widely reported
to potentially affect cancers. In this study, we conducted multiple bioinformatic analyses …

[HTML][HTML] Lidocaine suppresses viability and migration of human breast cancer cells: TRPM7 as a target for some breast cancer cell lines

H Liu, JP Dilger, J Lin - Cancers, 2021 - mdpi.com
Dilger … Liu, H.; Dilger, JP; Lin, J. Effects of local anesthetics on cancer cells. Pharmacol. …
Liu H, Dilger JP, Lin J. Lidocaine Suppresses Viability and Migration of Human Breast …

[HTML][HTML] The role of transient receptor potential melastatin 7 (TRPM7) in cell viability: a potential target to suppress breast cancer cell cycle

H Liu, JP Dilger, J Lin - Cancers, 2020 - mdpi.com
The divalent cation-selective channel transient receptor potential melastatin 7 (TRPM7) channel
was shown to affect the proliferation of some types of cancer cell. However, the function …