The α 2 and β 2 adrenergic receptors, both of which are activated by epinephrine, but which
can be differentiated by selective drugs, have opposite effects (inhibitory and stimulatory) on …

… We have recently proposed a mechanism (Fujino and Regan, 2003) that could explain how the
EP 4 receptor could induce the expression of … Fujino and Regan, 2003 … Fujino, JW Regan …

The gene for the human platelet α 2 -adrenergic receptor has been cloned with oligonucleotides
corresponding to the partial amino acid sequence of the purified receptor. The identity …

Dietary fish oil containing ω3 highly unsaturated fatty acids has cardioprotective and anti-inflammatory
effects. Prostaglandins (PGs) and thromboxanes are produced in vivo both from …

A cDNA that when expressed has the binding and functional characteristics of the pharmacologically
defined EP2 prostaglandin (PG) receptor [Cardiovasc. Drug Rev. 11:165-179 (1993…

Recently we have shown that the FP B prostanoid receptor, a G-protein-coupled receptor
that couples to Gα q , activates T-cell factor (Tcf)/lymphoid enhancer factor (Lef)-mediated …

Prostaglandin E 2 (PGE 2 ) mediates its physiological effects by interactions with a subfamily
of G-protein-coupled receptors known as EP receptors. These receptors consist of four …

An alpha 2-adrenergic receptor subtype has been cloned from a human kidney cDNA
library using the gene for the human platelet alpha 2-adrenergic receptor as a probe. The …

Numerous plasma membrane-bound receptors are coupled to various effectors via a family
of guanine nucleotide regulatory proteins (G proteins). Amino acid sequences of these …

Recent evidence suggests that many signaling molecules localize in microdomains of the
plasma membrane, particularly caveolae. In this study, overexpression of adenylyl cyclase …