The anti‐diabetic effect of anthocyanins in streptozotocin‐induced diabetic rats through glucose transporter 4 regulation and prevention of insulin resistance and …

…, SC Shin, SJ Lee, HG Seo, JH Lee… - Molecular nutrition & …, 2009 - Wiley Online Library
Hyperglycemia, abnormal lipid and antioxidant profiles are the most usual complications in
diabetes mellitus. Thus, in this study, we investigated the anti‐diabetic and anti‐oxidative …

Heme-oxygenase-1 induction and carbon monoxide-releasing molecule inhibit lipopolysaccharide (LPS)-induced high-mobility group box 1 release in vitro and …

K Tsoyi, TY Lee, YS Lee, HJ Kim, HG Seo, JH Lee… - Molecular …, 2009 - ASPET
We examined our hypothesis that heme-oxygenase-1 (HO-1)-derived carbon monoxide (CO)
inhibits the release of high-mobility group box 1 (HMGB1) in RAW264.7 cells activated with …

Metformin inhibits HMGB1 release in LPS‐treated RAW 264.7 cells and increases survival rate of endotoxaemic mice

…, YS Lee, HJ Kim, HG Seo, JH Lee… - British journal of …, 2011 - Wiley Online Library
BACKGROUND AND PURPOSE Recently, metformin, a well‐known anti‐diabetic drug, has
been shown to possess anti‐inflammatory activities. This study investigated the effect of …

Impaired D2 dopamine receptor function in mice lacking type 5 adenylyl cyclase

KW Lee, JH Hong, IY Choi, Y Che, JK Lee… - Journal of …, 2002 - Soc Neuroscience
Dopamine receptor subtypes D 1 and D 2 , and many other seven-transmembrane receptors
including adenosine receptor A 2A , are colocalized in striatum of brain. These receptors …

Anthocyanins from black soybean seed coats stimulate wound healing in fibroblasts and keratinocytes and prevent inflammation in endothelial cells

…, JI Chung, SC Shin, YK Jeong, HG Seo, JH Lee… - Food and Chemical …, 2009 - Elsevier
Wound healing is a complex process that includes inflammation, tissue formation, and
remodeling. While wound healing is accompanied by inflammatory reactions, chronic …

Hepatic ischemia/reperfusion in rats induces iNOS gene transcription by activation of NF-κB

…, HY Yun, BH Jeon, YM Kim, JH Seok, JH Lee - Biochemical and …, 1999 - Elsevier
It has been known that many immediately early genes are expressed during ischemia/reperfusion
(I/R) injury. Here, employing a model of hepatic I/R, we show that inducible nitric oxide …

2-methoxycinnamaldehyde from Cinnamomum cassia reduces rat myocardial ischemia and reperfusion injury in vivo due to HO-1 induction

JS Hwa, YC Jin, YS Lee, YS Ko, YM Kim, LY Shi… - Journal of …, 2012 - Elsevier
ETHNOPHARMACOLOGICAL RELEVANCE: Cinnamomum cassia Blume has been used
as a traditional Chinese herbal medicine for alleviation of fever, inflammation, chronic …

Tanshinone I suppresses growth and invasion of human breast cancer cells, MDA-MB-231, through regulation of adhesion molecules

IT Nizamutdinova, GW Lee, JS Lee, MK Cho… - …, 2008 - academic.oup.com
The role of cell adhesion molecules has been studied extensively in the process of inflammation,
and these molecules are critical components of carcinogenesis and cancer metastasis. …

Anthocyanins from Black Soybean Seed Coats Inhibit UVB-Induced Inflammatory Cylooxygenase-2 Gene Expression and PGE2 Production through Regulation of the …

…, SC Shin, WS Lee, HG Seo, JH Lee… - Journal of agricultural …, 2008 - ACS Publications
Ultraviolet (UV) radiation can cause inflammatory changes and may further contribute to
skin carcinogenesis. Anthocyanins are known to be powerful antioxidants that help protect …

Daidzein administration in vivo reduces myocardial injury in a rat ischemia/reperfusion model by inhibiting NF-kB activation

…, YC Jin, YM Kim, S Rhie, HJ Kim, HG Seo, JH Lee… - Life sciences, 2009 - Elsevier
AIMS: We tested the hypothesis that daidzein may reduce myocardial damage by both
inhibiting the release of cytokines and limiting the nuclear translocation of NF-kB. MAIN …