Teleosts lack a hypophyseal portal system and hence neurohormones are carried by nerve
fibers from the preoptic region to the pituitary. The various cell types in the teleost pituitary …

The zebrafish has become an important vertebrate model for basic and biomedical research,
including the research field of the biology of reproduction. However, very few …

Functional in vitro and in vivo reporter gene assays have recently been developed for the
rapid determination of exposure to (xeno)estrogens. The in vitro estrogen receptor (ER)-…

Large lipid transfer proteins (LLTP) are nonexchangeable apolipoproteins and intracellular
lipid-exchange proteins involved in the assembly, secretion, and metabolism of lipoproteins. …

Germ cell survival and development critically depend on the cells’ contact with Sertoli cells
in the vertebrate testis. Fish and amphibians are different from mammals in that they show a …

Background Spermatogonial stem cells (SSCs) are the foundation of spermatogenesis, and
reside within a specific microenvironment in the testes called “niche” which regulates stem …

Growth factors modulate germ line stem cell self-renewal and differentiation behavior. We
investigate the effects of Igf3, a fish-specific member of the igf family. Fsh increased in a steroid…

Dmrt1 and amh are genes involved in vertebrate sex differentiation. In this study, we cloned
dmrt1 and amh cDNAs in zebrafish (Danio rerio) and investigated the effects of exposure to …

This study aimed to improve, using the zebrafish model, our understanding of the distinct
roles of pituitary gonadotropins FSH and LH in regulating testis functions in teleost fish. We …

It has been proposed recently that two types of GnRH receptors (GnRHR) exist in a particular
species. Here we present data demonstrating that at least three types of GnRHR are …