The extensive world-wide morbidity and mortality caused by influenza A viruses highlights
the need for new insights into the host immune response and novel treatment approaches. …

The molecular composition and binding epitopes of the immunoglobulin G (IgG) antibodies
that circulate in blood plasma after severe acute respiratory syndrome coronavirus 2 (SARS-…

A complementary DNA (cDNA) for ubiquitin carboxyl-terminal hydrolase isozyme L3 was
cloned from human B cells. The cDNA encodes a protein of 230 amino acids with a molecular …

Cathelicidin LL-37 is one of the few human bactericidal peptides with potent antistaphylococcal
activity. In this study we examined the susceptibility of LL-37 to proteolytic degradation …

Thioredoxin (Trx1) is a redox-active protein containing two active site cysteines (Cys-32 and
Cys-35) that cycle between the dithiol and disulfide forms as Trx1 reduces target proteins. …

Antibiotic resistance is a major public health threat, further complicated by unexplained
treatment failures caused by bacteria that appear antibiotic susceptible. We describe an …

In a search for direct evidence leading to the biological relevance of airway secretions in
innate host defense, we characterized the antibacterial function of cationic polypeptides within …

Members of the heat-shock protein family (hsp70s) can distinguish folded from unfolded
proteins. This property is crucial to the role of hsp70s as molecular chaperones and is …

Fragile X mental retardation protein, FMRP, is absent in patients with fragile X syndrome, a
common form of mental retardation. FMRP is a nucleocytoplasmic RNA binding protein that is …

14-3-3 proteins bind a variety of molecules involved in signal transduction, cell cycle regulation
and apoptosis. 14-3-3 binds ligands such as Raf-1 kinase and Bad by recognizing the …