Interference with Sin3 function induces epigenetic reprogramming and differentiation in breast cancer cells

…, K Petrie, B Leibovitch, J Murtagh… - Proceedings of the …, 2010 - National Acad Sciences
Sin3A/B is a master transcriptional scaffold and corepressor that plays an essential role in
the regulation of gene transcription and maintenance of chromatin structure, and its …

Organization of mammary epithelial cells into 3D acinar structures requires glucocorticoid and JNK signaling

J Murtagh, E McArdle, E Gilligan, L Thornton… - The Journal of cell …, 2004 - rupress.org
Mammary epithelial cells cultured on a concentrated laminin-rich extracellular matrix formed
3D acinar structures that matured to polarized monolayers surrounding a lumen. In the …

[HTML][HTML] Maternal vaccination as an essential component of life-course immunization and its contribution to preventive neonatology

N Bergin, J Murtagh, RK Philip - International Journal of Environmental …, 2018 - mdpi.com
Maternal immunisation schedules are increasingly coming under the spotlight as part of the
development of lifetime immunisation programmes for the role that they play in improving …

Taxotere-induced inhibition of human endothelial cell migration is a result of heat shock protein 90 degradation

J Murtagh, H Lu, EL Schwartz - Cancer research, 2006 - AACR
In addition to effects on tumor cell proliferation and apoptosis, microtubule-binding agents
are potent inhibitors of angiogenesis. The cancer chemotherapeutic drug Taxotere (docetaxel) …

The microtubule binding drug laulimalide inhibits vascular endothelial growth factor-induced human endothelial cell migration and is synergistic when combined with …

H Lu, J Murtagh, EL Schwartz - Molecular pharmacology, 2006 - ASPET
Laulimalide, a natural product from marine sponges, is a microtubule-stabilizing agent that
binds to tubulin at a site distinct from that of the taxoids. In the present study, we found that …

[HTML][HTML] Assessment of dietary intake using food photography and video recording in free-living young adults: a comparative study

…, K Fleming, B Nichols, E Burleigh, J Murtagh… - Journal of the Academy …, 2021 - Elsevier
Background Conventional methods of dietary assessment are prone to recall bias and
place burden on participants. Objective Our aim was to compare the performance of image-based …

The Nuclear Factor I (NFI) gene family in mammary gland development and function

J Murtagh, F Martin, RM Gronostajski - Journal of mammary gland biology …, 2003 - Springer
Mammary gland development and function require the coordinated spatial and temporal
expression of a large fraction of the mammalian genome. A number of site-specific transcription …

Real-world impact of rotavirus vaccination in European healthcare settings: a systematic literature review

…, C Mameli, U Sabale, J Murtagh… - Expert Review of …, 2022 - Taylor & Francis
Introduction Rotavirus is one of the most common pathogens causing diarrhea in children <5
years and has a major impact on childhood morbidity and mortality. Since the …

[HTML][HTML] Transcription factor NFIC undergoes N-glycosylation during early mammary gland involution

R Kane, J Murtagh, D Finlay, A Marti, R Jaggi… - Journal of Biological …, 2002 - ASBMB
Expression of a 74-kDa nuclear factor I (NFI) protein is triggered in early involution in the
mouse mammary gland, and its expression correlates with enhanced occupation of a twin (NFI) …

[HTML][HTML] Impact assessment of immunization and the COVID-19 pandemic on varicella across Europe using digital epidemiology methods: A descriptive study

U Sabale, L Jarmale, J Murtagh, M Pawaskar… - Plos one, 2023 - journals.plos.org
Background Varicella is usually a mild disease in children but may be life-threatening,
especially in adolescents and adults. Infection control measures implemented during the …