Expression and 1, 4-dihydropyridine-binding properties of brain L-type calcium channel isoforms
…, C Wild, GJ Obermair, U Einzinger, JC Hoda… - Molecular …, 2009 - ASPET
The L-type calcium channel (LTCC) isoforms Ca v 1.2 and Ca v 1.3 display similar 1,4-dihydropyridine
(DHP) binding properties and are both expressed in mammalian brain. Recent …
(DHP) binding properties and are both expressed in mammalian brain. Recent …
[HTML][HTML] Modulation of voltage-and Ca2+-dependent gating of CaV1. 3 L-type calcium channels by alternative splicing of a C-terminal regulatory domain
…, MJ Sinnegger-Brauns, C Poggiani, JC Hoda… - Journal of biological …, 2008 - ASBMB
Low voltage activation of Ca V 1.3 L-type Ca 2+ channels controls excitability in sensory
cells and central neurons as well as sinoatrial node pacemaking. Ca V 1.3-mediated …
cells and central neurons as well as sinoatrial node pacemaking. Ca V 1.3-mediated …
α7 neuronal nicotinic acetylcholine receptors are negatively regulated by tyrosine phosphorylation and Src-family kinases
…, A Wiesner, KH Huh, R Ogier, JC Hoda… - Journal of …, 2005 - Soc Neuroscience
Nicotine, a component of tobacco, is highly addictive but possesses beneficial properties such
as cognitive improvements and memory maintenance. Involved in these processes is the …
as cognitive improvements and memory maintenance. Involved in these processes is the …
C-terminal modulator controls Ca2+-dependent gating of Cav1.4 L-type Ca2+ channels
A Singh, D Hamedinger, JC Hoda, M Gebhart… - Nature …, 2006 - nature.com
Tonic neurotransmitter release at sensory cell ribbon synapses is mediated by calcium (Ca 2+
) influx through L-type voltage-gated Ca 2+ channels. This tonic release requires the …
) influx through L-type voltage-gated Ca 2+ channels. This tonic release requires the …
A CACNA1F mutation identified in an X-linked retinal disorder shifts the voltage dependence of Cav1.4 channel activation
…, GM Clover, JC Hoda… - Proceedings of the …, 2005 - National Acad Sciences
Light stimuli produce graded hyperpolarizations of the photoreceptor plasma membrane
and an associated decrease in a voltagegated calcium channel conductance that mediates …
and an associated decrease in a voltagegated calcium channel conductance that mediates …
Cav1. 4α1 subunits can form slowly inactivating dihydropyridine-sensitive L-type Ca2+ channels lacking Ca2+-dependent inactivation
A Koschak, D Reimer, D Walter, JC Hoda… - Journal of …, 2003 - Soc Neuroscience
The neuronal L-type calcium channels (LTCCs) Ca v 1.2α1 and Ca v 1.3α1 are functionally
distinct. Ca v 1.3α1 activates at lower voltages and inactivates more slowly than Ca v 1.2α1, …
distinct. Ca v 1.3α1 activates at lower voltages and inactivates more slowly than Ca v 1.2α1, …
Cav1.3 (α1D) Ca2+ Currents in Neonatal Outer Hair Cells of Mice
M Michna, M Knirsch, JC Hoda… - The Journal of …, 2003 - Wiley Online Library
Outer hair cells (OHC) serve as electromechanical amplifiers that guarantee the unique
sensitivity and frequency selectivity of the mammalian cochlea. It is unknown whether the …
sensitivity and frequency selectivity of the mammalian cochlea. It is unknown whether the …
Congenital stationary night blindness type 2 mutations S229P, G369D, L1068P, and W1440X alter channel gating or functional expression of Cav1. 4 L-type Ca2+ …
JC Hoda, F Zaghetto, A Koschak… - Journal of …, 2005 - Soc Neuroscience
Mutations in the CACNA1F gene (voltage-dependent L-type calcium channel α1F subunit)
encoding retinal Ca v 1.4 L-type Ca 2+ channels cause X-linked recessive congenital …
encoding retinal Ca v 1.4 L-type Ca 2+ channels cause X-linked recessive congenital …
Human nocturnal frontal lobe epilepsy: pharmocogenomic profiles of pathogenic nicotinic acetylcholine receptor β-subunit mutations outside the ion channel pore
JC Hoda, W Gu, M Friedli, HA Phillips, S Bertrand… - Molecular …, 2008 - ASPET
Certain mutations in specific parts of the neuronal nicotinic acetylcholine receptor (nAChR)
subunit genes CHRNA4, CHRNB2, and probably CHRNA2, can cause autosomal dominant …
subunit genes CHRNA4, CHRNB2, and probably CHRNA2, can cause autosomal dominant …
[HTML][HTML] Mutations in familial nocturnal frontal lobe epilepsy might be associated with distinct neurological phenotypes
OK Steinlein, JC Hoda, S Bertrand, D Bertrand - Seizure, 2012 - Elsevier
Autosomal dominant nocturnal frontal lobe epilepsy (ADNFLE) is a rare familial seizure
disorder caused by mutations in at least two different subunit genes of the neuronal nicotinic …
disorder caused by mutations in at least two different subunit genes of the neuronal nicotinic …