[HTML][HTML] A human breast cancer-derived xenograft and organoid platform for drug discovery and precision oncology

…, J Toner, G Wang, Y Qiao, X Huang, JA Greenland… - Nature cancer, 2022 - nature.com
Abstract Models that recapitulate the complexity of human tumors are urgently needed to
develop more effective cancer therapies. We report a bank of human patient-derived xenografts …

Endoxifen, 4-hydroxytamoxifen and an estrogenic derivative modulate estrogen receptor complex mediated apoptosis in breast cancer

…, P Fan, RF Curpan, DMQ Rincon, JA Greenland… - Molecular …, 2018 - ASPET
Estrogen therapy was used to treat advanced breast cancer in postmenopausal women for
decades until the introduction of tamoxifen. Resistance to long-term estrogen deprivation (…

The structure-function relationship of angular estrogens and estrogen receptor alpha to initiate estrogen-induced apoptosis in breast cancer cells

…, BM Broom, DMQ Rincon, JA Greenland… - Molecular …, 2020 - ASPET
High-dose synthetic estrogen therapy was the standard treatment of advanced breast cancer
for three decades until the discovery of tamoxifen. A range of substituted triphenylethylene …

Isotopic composition of xenon from a Greenland anorthosite

PM Jeffery - Nature, 1971 - nature.com
… The demonstrated presence of gas well type xenon in North America, Australia and
Greenland indicates that it may be present on a global scale in suitable trapping sites. This …

Anomalous neon and xenon in an Archaean anorthosite from West Greenland

S Azuma, M Ozima, H Hiyagon - Earth and planetary science letters, 1993 - Elsevier
… However, it is obvious that Zadnik and Jeffery's and our data cannot be explained by O and
Mg reactions only, and it is necessary to consider a fluorine reaction, if the data were to be …

Vegetation phenology in Greenland and links to cryospheric change

JA Thompson, LS Koenig - Annals of Glaciology, 2018 - cambridge.org
… large connection to the Greenlandic population through the … (SFPs) were causing Greenlandic
vegetation to dry out and … widespread the drying was across Greenland. We utilized a …

Range-wide regional assignment of Atlantic salmon (Salmo salar) using genome wide single-nucleotide polymorphisms

NW Jeffery, BF Wringe, MC McBride, LC Hamilton… - Fisheries …, 2018 - Elsevier
… A) Principal component analysis of 280 individual Atlantic salmon of known continental origin
from the West Greenland mixed-stock fishery using our panel of 96 SNPs. Inset shows the …

Radiogenic neon in an Archaean anorthosite

MG Zadnik, PM Jeffery - Chemical Geology: Isotope Geoscience Section, 1985 - Elsevier
The isotopic composition of Ne trapped in an Archaean anorthosite (age > 2.9 Ga) from the
Fiskenaesset Complex in west Greenland is highly anomalous in comparison to the …

The seesaw in winter temperatures between Greenland and northern Europe. Part I: General description

H Van Loon, JC Rogers - Monthly Weather Review, 1978 - journals.ametsoc.org
We have investigated the well-known tendency for winter temperatures to be low over
northern Europe when they are high over Greenland and the Canadian Arctic, and conversely. …

Comparison of novel risk markers for improvement in cardiovascular risk assessment in intermediate-risk individuals

…, CT Sibley, D O'Leary, JJ Carr, DC Goff, P Greenland… - Jama, 2012 - jamanetwork.com
Context Risk markers including coronary artery calcium, carotid intima–media thickness,
ankle-brachial index, brachial flow–mediated dilation, high-sensitivity C-reactive protein (CRP), …