User profiles for Jiejun Wu
jiejun wuJohnson and Johnson Verified email at its.jnj.com Cited by 2597 |
[HTML][HTML] Lactate inhibits lipolysis in fat cells through activation of an orphan G-protein-coupled receptor, GPR81
C Liu, J Wu, J Zhu, C Kuei, J Yu, J Shelton… - Journal of Biological …, 2009 - ASBMB
Lactic acid is a well known metabolic by-product of intense exercise, particularly under anaerobic
conditions. Lactate is also a key source of energy and an important metabolic substrate…
conditions. Lactate is also a key source of energy and an important metabolic substrate…
Oxysterols direct B-cell migration through EBI2
EBI2 (also called GPR183) is an orphan G-protein-coupled receptor that is highly expressed
in spleen and upregulated upon Epstein–Barr-virus infection 1 . Recent studies indicated …
in spleen and upregulated upon Epstein–Barr-virus infection 1 . Recent studies indicated …
Damping and sound absorption properties of particle reinforced Al matrix composite foams
W Jiejun, L Chenggong, W Dianbin… - Composites Science and …, 2003 - Elsevier
In this paper, the damping and sound absorption properties of A356/xSiC p composite foams
have been studied (x expresses SiC vol.%). The results show that the loss factor β of A356/…
have been studied (x expresses SiC vol.%). The results show that the loss factor β of A356/…
Oxysterols are agonist ligands of RORγt and drive Th17 cell differentiation
The RAR-related orphan receptor gamma t (RORγt) is a nuclear receptor required for generating
IL-17–producing CD4 + Th17 T cells, which are essential in host defense and may play …
IL-17–producing CD4 + Th17 T cells, which are essential in host defense and may play …
[HTML][HTML] INSL5 is a high affinity specific agonist for GPCR142 (GPR100)
…, C Kuei, S Sutton, J Chen, P Bonaventure, J Wu… - Journal of Biological …, 2005 - ASBMB
Insulin-like peptide 5 (INSL5) is a peptide that belongs to the relaxin/insulin family, and its
receptor has not been identified. In this report, we demonstrate that INSL5 is a specific agonist …
receptor has not been identified. In this report, we demonstrate that INSL5 is a specific agonist …
Modulation of DNA methylation by a sesquiterpene lactone parthenolide
Z Liu, S Liu, Z Xie, RE Pavlovicz, J Wu, P Chen… - … of Pharmacology and …, 2009 - ASPET
Hypermethylation of 5′-cytosine-guanosine islands of tumor suppressor genes resulting in
their silencing has been proposed to be a hallmark of various tumors. Modulation of DNA …
their silencing has been proposed to be a hallmark of various tumors. Modulation of DNA …
Commensal bacteria contribute to insulin resistance in aging by activating innate B1a cells
Aging in humans is associated with increased hyperglycemia and insulin resistance (collectively
termed IR) and dysregulation of the immune system. However, the causative factors …
termed IR) and dysregulation of the immune system. However, the causative factors …
Directed remodeling of the mouse gut microbiome inhibits the development of atherosclerosis
…, NE Moore, GR Aleman Muench, J Wu… - Nature …, 2020 - nature.com
The gut microbiome is a malleable microbial community that can remodel in response to
various factors, including diet, and contribute to the development of several chronic diseases, …
various factors, including diet, and contribute to the development of several chronic diseases, …
[HTML][HTML] R3 (BΔ23–27) R/I5 chimeric peptide, a selective antagonist for GPCR135 and GPCR142 over relaxin receptor LGR7: In vitro and in vivo characterization
…, J Shelton, J Zhu, D Nepomuceno, J Wu… - Journal of Biological …, 2007 - ASBMB
Both relaxin-3 and its receptor (GPCR135) are expressed predominantly in brain regions
known to play important roles in processing sensory signals. Recent studies have shown that …
known to play important roles in processing sensory signals. Recent studies have shown that …
3, 5-Dihydroxybenzoic acid, a specific agonist for hydroxycarboxylic acid 1, inhibits lipolysis in adipocytes
…, MA Connelly, G Lee, N Carruthers, J Wu… - … of Pharmacology and …, 2012 - ASPET
Niacin raises high-density lipoprotein and lowers low-density lipoprotein through the activation
of the β-hydroxybutyrate receptor hydroxycarboxylic acid 2 (HCA2) (aka GPR109a) but …
of the β-hydroxybutyrate receptor hydroxycarboxylic acid 2 (HCA2) (aka GPR109a) but …