Local calcium transients triggered by single L-type calcium channel currents in cardiac cells
JR López-López, PS Shacklock, CW Balke, WG Wier - Science, 1995 - science.org
Excitation-contraction coupling was studied in mammalian cardiac cells in which the opening
probability of L-type calcium (Ca 2+ ) channels was reduced. Confocal microscopy during …
probability of L-type calcium (Ca 2+ ) channels was reduced. Confocal microscopy during …
[HTML][HTML] TRPA1 channels mediate acute neurogenic inflammation and pain produced by bacterial endotoxins
Gram-negative bacterial infections are accompanied by inflammation and somatic or
visceral pain. These symptoms are generally attributed to sensitization of nociceptors by …
visceral pain. These symptoms are generally attributed to sensitization of nociceptors by …
Chemotransduction in the Carotid Body: K+ Current Modulated by PO2 In Type I Chemoreceptor Cells
The ionic currents of carotid body type I cells and their possible involvement in the detection
of oxygen tension (PO 2 ) in arterial blood are unknown. The electrical properties of these …
of oxygen tension (PO 2 ) in arterial blood are unknown. The electrical properties of these …
O2 Modulates Large-Conductance Ca2+-Dependent K+ Channels of Rat Chemoreceptor Cells by a Membrane-Restricted and CO-Sensitive Mechanism
AM Riesco-Fagundo, MT Pérez-García… - Circulation …, 2001 - Am Heart Assoc
… To date, apart of this study, the only attempt of investigating the effects of lowering O 2 in the
gating properties of a K + channel has been the work of Ganfornina and López-Barneo 2 on …
gating properties of a K + channel has been the work of Ganfornina and López-Barneo 2 on …
Kvβ1.2 Subunit Coexpression in HEK293 Cells Confers O2 Sensitivity to Kv4.2 but not to Shaker Channels
MT Pérez-García, JR López-López… - The Journal of general …, 1999 - rupress.org
Voltage-gated K + (K V ) channels are protein complexes composed of ion-conducting integral
membrane α subunits and cytoplasmic modulatory β subunits. The differential expression …
membrane α subunits and cytoplasmic modulatory β subunits. The differential expression …
The secret life of ion channels: Kv1. 3 potassium channels and proliferation
…, P Cidad, JR López-López - American Journal of …, 2018 - journals.physiology.org
Kv1.3 channels are involved in the switch to proliferation of normally quiescent cells, being
implicated in the control of cell cycle in many different cell types and in many different ways. …
implicated in the control of cell cycle in many different cell types and in many different ways. …
Pharmacologic and functional characterization of malignant hyperthermia in the R163C RyR1 knock-in mouse
Background Malignant hyperthermia is a pharmacogenetic disorder affecting humans, dogs,
pigs, and horses. In the majority of human cases and all cases in animals, malignant …
pigs, and horses. In the majority of human cases and all cases in animals, malignant …
Kv1. 3 channels can modulate cell proliferation during phenotypic switch by an ion-flux independent mechanism
…, C Ruiz-McDavitt, JR López-López… - … , and vascular biology, 2012 - Am Heart Assoc
Objective— Phenotypic modulation of vascular smooth muscle cells has been associated
with a decreased expression of all voltage-dependent potassium channel (Kv)1 channel …
with a decreased expression of all voltage-dependent potassium channel (Kv)1 channel …
[HTML][HTML] Altered ROS production, NF-κB activation and interleukin-6 gene expression induced by electrical stimulation in dystrophic mdx skeletal muscle cells
Duchenne muscular dystrophy is a fatal X-linked genetic disease, caused by mutations in
the dystrophin gene, which cause functional loss of this protein. This pathology is associated …
the dystrophin gene, which cause functional loss of this protein. This pathology is associated …
Characterization of the Kv channels of mouse carotid body chemoreceptor cells and their role in oxygen sensing
…, JR López‐López - The Journal of …, 2004 - Wiley Online Library
As there are wide interspecies variations in the molecular nature of the O 2 ‐sensitive Kv
channels in arterial chemoreceptors, we have characterized the expression of these channels …
channels in arterial chemoreceptors, we have characterized the expression of these channels …