Local calcium transients triggered by single L-type calcium channel currents in cardiac cells
JR López-López, PS Shacklock, CW Balke, WG Wier - Science, 1995 - science.org
Excitation-contraction coupling was studied in mammalian cardiac cells in which the opening
probability of L-type calcium (Ca 2+ ) channels was reduced. Confocal microscopy during …
probability of L-type calcium (Ca 2+ ) channels was reduced. Confocal microscopy during …
Chemotransduction in the Carotid Body: K+ Current Modulated by PO2 In Type I Chemoreceptor Cells
The ionic currents of carotid body type I cells and their possible involvement in the detection
of oxygen tension (PO 2 ) in arterial blood are unknown. The electrical properties of these …
of oxygen tension (PO 2 ) in arterial blood are unknown. The electrical properties of these …
Local control of excitation‐contraction coupling in rat heart cells.
1. Cytosolic free calcium ion concentration ([Ca2+]i) and whole‐cell L‐type Ca2+ channel
currents were measured during excitation‐contraction (E‐C) coupling in single voltage‐…
currents were measured during excitation‐contraction (E‐C) coupling in single voltage‐…
Validity of real time ultrasound in the diagnosis of hepatic steatosis: a prospective study
…, J Dasarathy, A Khiyami, R Joseph, R Lopez… - Journal of …, 2009 - Elsevier
BACKGROUND/AIMS: Ultrasound is used to screen for hepatic steatosis, the most common
liver disease in the United States. However, few studies have prospectively evaluated the …
liver disease in the United States. However, few studies have prospectively evaluated the …
[HTML][HTML] TRPA1 channels mediate acute neurogenic inflammation and pain produced by bacterial endotoxins
Gram-negative bacterial infections are accompanied by inflammation and somatic or
visceral pain. These symptoms are generally attributed to sensitization of nociceptors by …
visceral pain. These symptoms are generally attributed to sensitization of nociceptors by …
Increased intraneuronal resting [Ca2+] in adult Alzheimer's disease mice
JR Lopez, A Lyckman, S Oddo… - Journal of …, 2008 - Wiley Online Library
Neurodegeneration in Alzheimer’s disease (AD) has been linked to intracellular accumulation
of misfolded proteins and dysregulation of intracellular Ca 2+ . In the current work, we …
of misfolded proteins and dysregulation of intracellular Ca 2+ . In the current work, we …
Transpiration increases under high‐temperature stress: Potential mechanisms, trade‐offs and prospects for crop resilience in a warming world
The frequency and intensity of high‐temperature stress events are expected to increase as
climate change intensifies. Concomitantly, an increase in evaporative demand, driven in part …
climate change intensifies. Concomitantly, an increase in evaporative demand, driven in part …
Pharmacologic and functional characterization of malignant hyperthermia in the R163C RyR1 knock-in mouse
Background Malignant hyperthermia is a pharmacogenetic disorder affecting humans, dogs,
pigs, and horses. In the majority of human cases and all cases in animals, malignant …
pigs, and horses. In the majority of human cases and all cases in animals, malignant …
Enhanced excitation-coupled calcium entry in myotubes expressing malignant hyperthermia mutation R163C is attenuated by dantrolene
Dantrolene is the drug of choice for the treatment of malignant hyperthermia (MH) and is
also useful for treatment of spasticity or muscle spasms associated with several clinical …
also useful for treatment of spasticity or muscle spasms associated with several clinical …
O2 Modulates Large-Conductance Ca2+-Dependent K+ Channels of Rat Chemoreceptor Cells by a Membrane-Restricted and CO-Sensitive Mechanism
AM Riesco-Fagundo, MT Pérez-García… - Circulation …, 2001 - Am Heart Assoc
Hypoxic inhibition of large-conductance Ca 2+ -dependent K + channels (maxiK) of rat carotid
body type I cells is a well-established fact. However, the molecular mechanisms of such …
body type I cells is a well-established fact. However, the molecular mechanisms of such …