Effector pathway-dependent relative efficacy at serotonin type 2A and 2C receptors: evidence for agonist-directed trafficking of receptor stimulus
KA Berg, S Maayani, J Goldfarb, C Scaramellini… - Molecular …, 1998 - ASPET
There are many examples of a single receptor coupling directly to more than one cellular
signal transduction pathway. Although traditional receptor theory allows for activation of …
signal transduction pathway. Although traditional receptor theory allows for activation of …
The Chinese herbal medicine formula FAHF-2 completely blocks anaphylactic reactions in a murine model of peanut allergy
…, JH Li, L Zhang, S Wallenstein, J Goldfarb… - Journal of Allergy and …, 2005 - Elsevier
BACKGROUND: Peanut allergy is potentially life threatening. There is no curative therapy
for this disorder. We previously found that an herbal formula, food allergy herbal formula (FAHF…
for this disorder. We previously found that an herbal formula, food allergy herbal formula (FAHF…
Systems biology primer: the basic methods and approaches
I Tavassoly, J Goldfarb, R Iyengar - Essays in biochemistry, 2018 - portlandpress.com
Systems biology is an integrative discipline connecting the molecular components within a
single biological scale and also among different scales (eg cells, tissues and organ systems) …
single biological scale and also among different scales (eg cells, tissues and organ systems) …
Systems pharmacology of adverse event mitigation by drug combinations
…, L Benard, JJ Badimon, RJ Hajjar, J Goldfarb… - Science translational …, 2013 - science.org
Drugs are designed for therapy, but medication-related adverse events are common, and
risk/benefit analysis is critical for determining clinical use. Rosiglitazone, an efficacious …
risk/benefit analysis is critical for determining clinical use. Rosiglitazone, an efficacious …
Licorice Flavonoids Inhibit Eotaxin-1 Secretion by Human Fetal Lung Fibroblasts in Vitro
…, R Wang, D Holmes, J Goldfarb… - Journal of agricultural …, 2009 - ACS Publications
Glycyrrhiza uralensis (Gan-Cao), commonly called “licorice”, is one of the most commonly
used herbs in traditional Chinese medicine (TCM). In the United States, licorice products are …
used herbs in traditional Chinese medicine (TCM). In the United States, licorice products are …
Glycyrrhiza uralensis Flavonoids Present in Anti‐Asthma Formula, ASHMITM, Inhibit Memory Th2 Responses in Vitro and in Vivo
…, J Bolleddula, S Doddaga, J Goldfarb… - Phytotherapy …, 2013 - Wiley Online Library
Allergic asthma is associated with Th2‐mediated inflammation. Several flavonoids were
isolated from Glycyrrhiza uralensis, one of the herbs in the anti‐asthma herbal medicine …
isolated from Glycyrrhiza uralensis, one of the herbs in the anti‐asthma herbal medicine …
Network analysis of FDA approved drugs and their targets
A Ma'ayan, SL Jenkins, J Goldfarb… - Mount Sinai Journal of …, 2007 - Wiley Online Library
The global relationship between drugs that are approved for therapeutic use and the human
genome is not known. We employed graph‐theory methods to analyze the Federal Food …
genome is not known. We employed graph‐theory methods to analyze the Federal Food …
Food Allergy Herbal Formula-2 silences peanut-induced anaphylaxis for a prolonged posttreatment period via IFN-γ–producing CD8+ T cells
KD Srivastava, C Qu, T Zhang, J Goldfarb… - Journal of Allergy and …, 2009 - Elsevier
BACKGROUND: Food allergy is a serious and sometimes fatal condition for which there is no
cure. We previously reported that Food Allergy Herbal Formula (FAHF)–2) protected peanut…
cure. We previously reported that Food Allergy Herbal Formula (FAHF)–2) protected peanut…
Ganoderic acid C1 isolated from the anti-asthma formula, ASHMI™ suppresses TNF-α production by mouse macrophages and peripheral blood mononuclear cells …
…, D Weir, J Tversky, RL Miller, J Goldfarb… - International …, 2015 - Elsevier
Asthma is a heterogeneous airway inflammatory disease, which is associated with Th2
cytokine-driven inflammation and non-Th2, TNF-α mediated inflammation. Unlike Th2 mediated …
cytokine-driven inflammation and non-Th2, TNF-α mediated inflammation. Unlike Th2 mediated …
[HTML][HTML] Transcriptomic profiling of human cardiac cells predicts protein kinase inhibitor-associated cardiotoxicity
…, B Hu, M Mahajan, JM Gallo, J Goldfarb… - Nature …, 2020 - nature.com
Kinase inhibitors (KIs) represent an important class of anti-cancer drugs. Although
cardiotoxicity is a serious adverse event associated with several KIs, the reasons remain poorly …
cardiotoxicity is a serious adverse event associated with several KIs, the reasons remain poorly …