Direct-acting cannabinoid receptor agonists are well known to reduce hyperalgesic responses
and allodynia after nerve injury, although their psychoactive side effects have damped …

… Justin Poklis … ZCZ011 (40 mg/kg) was detected in whole brain, 6.5±0.6 (mean±SEM) ng/wet
(g), as determined by HPLC/MS/MS (Poklis et al, 2015). Given alone, 40 mg/kg ZCZ011 did …

Background A new class of synthetic hallucinogens called NBOMe has emerged as drugs
of abuse. Objective Our aim was to conduct a systematic review of published reports of …

We present a traumatic fatality of a 19-year-old man who had ingested blotter paper
containing 25I-NBOMe [2-(4-iodo-2,5-dimethoxyphenyl)-N-[(2-methoxyphenyl)methyl]ethanamine]. …

Context. Abuse of synthetic stimulant compounds resulting in significant toxicity is being
increasingly reported by poison centers. Toxicologic assessment is complicated by inconsistent …

In recent years, N-methoxybenzyl-methoxyphenylethylamine (NBOMe) derivatives, a class
of designer hallucinogenic drugs, have become popular drugs of abuse. These drugs have …

The present study tested a hypothesis that excess accumulation of sphingolipid, ceramide,
its metabolites, or a combination contributes to the development of obesity and associated …

Personal battery-powered vaporizers or electronic cigarettes were developed to deliver a
nicotine vapor such that smokers could simulate smoking tobacco without the inherent …

Heroin is a highly abused opioid and incurs a significant detriment to society worldwide. In
an effort to expand the limited pharmacotherapy options for opioid use disorders, a heroin …

In the last two years, an epidemic of fatal narcotic overdose cases has occurred in the Tampa
area of Florida. Fourteen of these deaths involved fentanyl and/or the new designer drug, …