Antimalarial artemisinin drugs induce cytochrome P450 and MDR1 expression by activation of xenosensors pregnane X receptor and constitutive androstane receptor
O Burk, KA Arnold, AK Nussler, E Schaeffeler… - Molecular …, 2005 - ASPET
Artemisinin drugs are of utmost importance in the treatment of malaria, because they represent
the sole class of therapeutically used antimalarial drugs to which malaria parasites have …
the sole class of therapeutically used antimalarial drugs to which malaria parasites have …
A role for constitutive androstane receptor in the regulation of human intestinal MDR1 expression
O Burk, KA Arnold, A Geick, H Tegude, M Eichelbaum - 2005 - degruyter.com
MDR1/P-glycoprotein is an efflux transporter determining the absorption and presystemic
elimination of many xenobiotics in the gut. Thus, interindividual differences in MDR1 …
elimination of many xenobiotics in the gut. Thus, interindividual differences in MDR1 …
Association of genetic polymorphism in ABCC2 with hepatic multidrug resistance-associated protein 2 expression and pravastatin pharmacokinetics
M Niemi, KA Arnold, JT Backman… - Pharmacogenetics …, 2006 - journals.lww.com
Objective Our aim was to investigate possible effects of sequence variations in ABCC2,
encoding the multidrug resistance-associated protein 2 (MRP2), on the pharmacokinetics of the …
encoding the multidrug resistance-associated protein 2 (MRP2), on the pharmacokinetics of the …
Impact of the SLCO1B1 polymorphism on the pharmacokinetics and lipid‐lowering efficacy of multiple‐dose pravastatin
M Igel, KA Arnold, M Niemi, U Hofmann… - Clinical …, 2006 - Wiley Online Library
Background and Objective The polymorphism of SLCO1B1 (solute carrier organic anion
transporter family, member 1B1), encoding the hepatic uptake transporter organic anion …
transporter family, member 1B1), encoding the hepatic uptake transporter organic anion …
Disposition of oral and intravenous pravastatin in MRP2-deficient TR–rats
…, K Meissner, KU Möritz, C Ritter, KA Arnold… - Drug Metabolism and …, 2005 - ASPET
The aim of this study was to characterize the role of the efflux transporter Mrp2 (Abcc2) in
the pharmacokinetics of orally and intravenously administered pravastatin in rats. Eight Mrp2-…
the pharmacokinetics of orally and intravenously administered pravastatin in rats. Eight Mrp2-…
[HTML][HTML] 27 Feb VisionHealth raises 3 million Euro to finance extended COPD and asthma study
K Arnold, B Keller - visionhealth.gmbh
Munich (Germany), February 27, 2023–VisionHealth GmbH, a pioneer in digital therapeutics
(DTx) to enhance inhaled treatment of chronic lung diseases, today announced the …
(DTx) to enhance inhaled treatment of chronic lung diseases, today announced the …
[HTML][HTML] EQS-News: VisionHealth raises 3 million Euro to finance extended COPD and asthma study for market preparation of Kata®, an innovative digital therapeutic …
K Arnold, B Keller - centralcharts.com
Munich (Germany), February 27, 2023–VisionHealth GmbH, a pioneer in digital therapeutics
(DTx) to enhance inhaled treatment of chronic lung diseases, today announced the …
(DTx) to enhance inhaled treatment of chronic lung diseases, today announced the …
[HTML][HTML] VISIONHEALTH GMBH VisionHealth and Boehringer Ingelheim: Digital therapy support for asthma and COPD
K Arnold, B Keller - webdisclosure.com
Munich, July 12th, 2022–VisionHealth and Boehringer Ingelheim will cooperate on the Kata®
app for therapy support in asthma and chronic obstructive pulmonary disease (COPD). …
app for therapy support in asthma and chronic obstructive pulmonary disease (COPD). …
[HTML][HTML] VISIONHEALTH GMBH EQS-News: VisionHealth raises 3 million Euro to finance extended COPD and asthma study for market preparation of Kata®, an …
K Arnold, B Keller - webdisclosure.com
Munich (Germany), February 27, 2023–VisionHealth GmbH, a pioneer in digital therapeutics
(DTx) to enhance inhaled treatment of chronic lung diseases, today announced the …
(DTx) to enhance inhaled treatment of chronic lung diseases, today announced the …
[HTML][HTML] digital diagnostics
B Keller, K Arnold, E Viragh - life-sciences-france.com
Temedica GmbH, a leading digital health and health insights company, today announced its
cooperation with Bristol Myers Squibb to develop a digital companion for patients with …
cooperation with Bristol Myers Squibb to develop a digital companion for patients with …