Cytokine abundance in placental tissues: evidence of inflammatory activation in gestational membranes with term and preterm parturition

JA Keelan, KW Marvin, TA Sato, M Coleman… - American journal of …, 1999 - Elsevier
Objectives: This study of the changes in cytokine concentrations in gestational tissues from
women with term and preterm labor was undertaken to assess the extent of inflammatory …

UDP-glucuronosyltransferase activity, expression and cellular localization in human placenta at term

…, MD Tingle, M Blumenstein, KW Marvin… - Biochemical …, 2002 - Elsevier
The activity, expression and localization of the UDP-glucuronosyltransferases (UGTs) were
investigated in human placenta at term. UGT activity (measured with the substrate 4-…

Cornifin, a cross-linked envelope precursor in keratinocytes that is down-regulated by retinoids.

KW Marvin, MD George, W Fujimoto… - Proceedings of the …, 1992 - National Acad Sciences
In this study, we have characterized the cDNA clone SQ37 that was isolated previously from
a rabbit squamous cell library. The gene encodes a 14-kDa protein that appears to function …

15-Deoxy-Δ12, 14-prostaglandin J2, a ligand for peroxisome proliferator-activated receptor-γ, induces apoptosis in JEG3 choriocarcinoma cells

JA Keelan, TA Sato, KW Marvin, J Lander… - Biochemical and …, 1999 - Elsevier
Apoptosis has been described in placental (trophoblast) tissues during both normal and
abnormal pregnancies. We have studied the effects of the cyclopentenone prostaglandins (PGs) …

Expression of angiogenic and neurotrophic factors in the human amnion and choriodecidua

KW Marvin, JA Keelan, RL Eykholt, TA Sato… - American journal of …, 2002 - Elsevier
Objective: Our objective was to identify the novel or differential expression of growth or
development associated genes in the human gestational membranes that might play roles in …

Peroxisome proliferator-activated receptor isoform expression changes in human gestational tissues with labor at term

…, RS Gilmour, MD Mitchell, KW Marvin - Molecular …, 2003 - ASPET
Peroxisome proliferator-activated receptors (PPARs) are a family of nuclear receptors that
are involved in lipid metabolism, differentiation, proliferation, cell death, and inflammation. …

[HTML][HTML] Isolation and characterization of acetylated histones H3 and H4 and their assembly into nucleosomes.

KW Marvin, P Yau, EM Bradbury - Journal of Biological Chemistry, 1990 - Elsevier
Nucleosome and chromatin structure/function relationships of histone acetylations are not
understood. To address these questions we have developed chromatographic procedures …

[HTML][HTML] Identification and characterization of a novel squamous cell-associated gene related to PMP22

KW Marvin, W Fujimoto, AM Jetten - Journal of Biological Chemistry, 1995 - ASBMB
In this study, we identify and characterize a novel gene, CL-20, that encodes a 17.8-kDa
protein with sequence and structural similarity to the growth arrest-specific gene gas3/…

cDNA cloning, genomic structure, and chromosome mapping of the human epithelial membrane protein CL-20 gene (EMP1), a member of the PMP22 family

Y Chen, A Medvedev, P Ruzanov, KW Marvin… - Genomics, 1997 - Elsevier
CL-20is a novel gene encoding a protein that is structurally related to but distinct from the
peripheral myelin protein PMP22. Like PMP22, CL-20 is likely to play important roles in the …

Gestational age-dependent up-regulation of prostaglandin D synthase (PGDS) and production of PGDS-derived antiinflammatory prostaglandins in human placenta

RJA Helliwell, JA Keelan, KW Marvin… - The Journal of …, 2006 - academic.oup.com
Context: The importance of prostaglandin (PG) signaling pathways to the maintenance of
pregnancy and initiation of labor is well recognized. However, the complexity of these …