[HTML][HTML] Real-time visualization of the cellular redistribution of G protein-coupled receptor kinase 2 and β-arrestin 2 during homologous desensitization of the …

LS Barak, K Warabi, X Feng, MG Caron… - Journal of Biological …, 1999 - ASBMB
The substance P receptor (SPR) is a G protein-coupled receptor (GPCR) that plays a key role
in pain regulation. The SPR desensitizes in the continued presence of agonist, presumably …

Preoperative plasma brain natriuretic peptide level is an independent predictor of postoperative atrial fibrillation following off-pump coronary artery bypass surgery

T Akazawa, H Nishihara, H Iwata, K Warabi… - Journal of …, 2008 - Springer
Purpose Atrial fibrillation (AF) is a frequent complication after coronary artery bypass surgery.
Postoperative AF can lead to thromboembolic events, prolonged hospital stay, and …

Characterization of GRK2-catalyzed phosphorylation of the human substance P receptor in Sf9 membranes

K Nishimura, K Warabi, ED Roush, J Frederick… - Biochemistry, 1998 - ACS Publications
G protein-coupled receptor kinases (GRKs) phosphorylate agonist-occupied G protein-coupled
receptors (GPCRs), resulting in GPCR desensitization. GRK2 is one of the better studied …

Prospective study of antibiotic protocols for managing surgical site infections in children

S Ichikawa, M Ishihara, T Okazaki, K Warabi… - Journal of pediatric …, 2007 - Elsevier
PURPOSE: We adopted antibiotic (Ab) protocols for managing surgical site infections in
children and assessed their effectiveness. METHODS: We used our protocols on 1313 children …

Present status of preparatory measures for massive hemorrhage and emergency blood transfusion in regional hospitals with an accredited department of …

K Irita, E Inada, H Yoshimura, K Warabi… - Masui. The Japanese …, 2009 - europepmc.org
Background Annual surveys conducted by the Japanese Society of Anesthesiologists
repeatedly show that hemorrhage is the leading cause of life-threatening events in the operating …

Characterization of differences between rapid agonist-dependent phosphorylation and phorbol ester-mediated phosphorylation of human substance P receptor in …

ED Roush, K Warabi, MM Kwatra - Molecular pharmacology, 1999 - ASPET
Substance P receptor (SPR), which plays a key role in pain transmission, is known to undergo
rapid agonist-dependent desensitization and internalization. The present study shows that …

The degree of newly emerging mitral regurgitation during off-pump coronary artery bypass is predicted by preoperative left ventricular function

T Akazawa, H Iizuka, M Aizawa, K Warabi… - Journal of …, 2008 - Springer
Purpose During off-pump coronary artery bypass (OPCAB), the displacement of the heart
causes mitral regurgitation. We hypothesized that patients with impaired left ventricle (LV) …

[HTML][HTML] Human substance P receptor undergoes agonist-dependent phosphorylation by G protein-coupled receptor kinase 5 in vitro

K Warabi, MD Richardson, WT Barry, K Yamaguchi… - FEBS letters, 2002 - Elsevier
G protein-coupled receptor kinases (GRKs) phosphorylate agonist-occupied G protein-coupled
receptors, leading to receptor desensitization. Seven GRKs, designated GRK1 through 7, …

Electrogastrography during and after cesarean delivery

M Oshima, K Aoyama, K Warabi, T Akazawa… - Journal of …, 2009 - Springer
Purpose Although it has been generally believed that parturients have delayed gastric emptying
during anesthesia, the most recent reports suggest that gastric emptying is not delayed …

A case of anaphylactic shock in an elderly man following protamine sulfate administration during emergent off-pump coronary artery bypass grafting

O Kudoh, K Warabi, K Yamaguchi… - Masui. The Japanese …, 2006 - europepmc.org
An 80-year-old diabetic man undergoing emergent off-pump coronary artery bypass grafting
for acute myocardial infarction developed anaphylactic shock immediately following …