Safety assessment of coenzyme Q10 (CoQ10)

T Hidaka, K Fujii, I Funahashi, N Fukutomi… - Biofactors, 2008 - Wiley Online Library
Coenzyme Q 10 (CoQ 10 ) is a naturally occurring component present in living cells. Its
physiological function is to act as an essential cofactor for ATP production, and to perform …

Study on safety and bioavailability of ubiquinol (Kaneka QH™) after single and 4-week multiple oral administration to healthy volunteers

K Hosoe, M Kitano, H Kishida, H Kubo, K Fujii… - Regulatory Toxicology …, 2007 - Elsevier
The safety and bioavailability of ubiquinol (the reduced form of coenzyme Q 10 ), a naturally
occurring lipid-soluble nutrient, were evaluated for the first time in single-blind, placebo-…

Validation of photoplethysmography as a method to detect heart rate during rest and exercise

…, Z Rosen, LL Litman, K Fujii - Journal of medical …, 2015 - Taylor & Francis
Despite their enhanced marketplace visibility, validity of wearable photoplethysmographic
heart rate monitoring is scarce. Forty-seven healthy participants performed seven, 6-min …

Safety assessment of coenzyme Q10 (Kaneka Q10) in healthy subjects: a double-blind, randomized, placebo-controlled trial

H Ikematsu, K Nakamura, S Harashima, K Fujii… - Regulatory Toxicology …, 2006 - Elsevier
The safety profile of Coenzyme Q10 (Kaneka Q10) at high doses for healthy subjects was
assessed in a double-blind, randomized, placebo-controlled study. Kaneka Q10 in capsule …

Poly (ethylene terephthalate) Nanofibers Made by Sea–Island‐Type Conjugated Melt Spinning and Laser‐Heated Flow Drawing

K Nakata, K Fujii, Y Ohkoshi, Y Gotoh… - Macromolecular …, 2007 - Wiley Online Library
Nylon‐6/poly(ethylene terephthalate) (PET) ultra‐multi‐island sea–island conjugated melt‐spun
fibers are flow‐drawn at a draw ratio of 174 with heating by CO 2 laser irradiation. …

Food content of ubiquinol-10 and ubiquinone-10 in the Japanese diet

H Kubo, K Fujii, T Kawabe, S Matsumoto… - Journal of Food …, 2008 - Elsevier
Seventy food items (8 types of meat, 16 types of fish and shellfish, 21 vegetables, 7 fruits, 6
pulses, 3 potatoes, 3 dairy products and 6 others) were analyzed using a simple and reliable …

Functional connections and pathways of coenzyme Q10‐inducible genes: An in‐silico study

F Döring, C Schmelzer, I Lindner, C Vock, K Fujii - IUBMB life, 2007 - Wiley Online Library
Coenzyme Q10 (CoQ10, ubiquinone) is an essential cofactor in the electron transport chain,
serves as a potent antioxidant in mitochondria and lipid membranes, and is often used as a …

Role of MGAT2 and DGAT1 in the release of gut peptides after triglyceride ingestion

M Okawa, K Fujii, K Ohbuchi, M Okumoto… - Biochemical and …, 2009 - Elsevier
Triglyceride ingestion releases gut peptides from enteroendocrine cells located in the
intestinal epithelia and provides feedback regulations of gastrointestinal function. The precise …

Reduced coenzyme Q10 supplementation decelerates senescence in SAMP1 mice

J Yan, K Fujii, J Yao, H Kishida, K Hosoe… - Experimental …, 2006 - Elsevier
The SAMP1 strain is a mouse model for accelerated senescence and severe senile
amyloidosis. We determined whether supplementation with coenzyme Q10 (CoQ10) could …

Estrogenic and dioxin-like potency in each step of a controlled landfill leachate treatment plant in Japan

PA Behnisch, K Fujii, K Shiozaki, I Kawakami, S Sakai - Chemosphere, 2001 - Elsevier
The estrogenic activity (by E-screen bioassay), the concentrations of PCBs, PCDDs/PCDFs (and
their resulting toxicity equivalents, TEQ) and several endocrine disrupting chemicals (…